• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种新型鼻内镜辅助方法用于封闭脑脊液鼻漏。

A Novel Nasal Endoscopy-Assisted Method for Sealing Cerebrospinal Fluid Rhinorrhea.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

J Craniofac Surg. 2024;35(5):1507-1508. doi: 10.1097/SCS.0000000000010278. Epub 2024 May 14.

DOI:10.1097/SCS.0000000000010278
PMID:39042072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11198945/
Abstract

Cerebrospinal fluid (CSF) rhinorrhea is one of the most common complications after trans-sphenoidal surgery. At present, transcranial or endoscopic surgery for CSF leakage requires general anesthesia to remove autologous fat or fascia to repair the leak, which is traumatic and costly. The authors present a case of a 25-year-old male patient with pituitary adenoma who experienced CSF rhinorrhea 10 days after undergoing endoscopic resection of the tumor. The authors innovatively sequential filled the leak with a gelatin sponge soaked in povidone-iodine solution and iodinated gauze under outpatient nasal endoscopy. The follow-up of 6 months showed no recurrence of CSF leakage. CSF leakage is the most common complication of trans-sphenoidal surgery. The authors suggest that for small cerebrospinal fluid leaks in the early stage after trans-sphenoidal surgery, the leakage should be first filled with gelatin sponge and iodoform gauze sequentially under outpatient nasal endoscopy, which may achieve a complete cure.

摘要

脑脊液(CSF)鼻漏是经蝶窦手术后最常见的并发症之一。目前,针对 CSF 漏的经颅或内镜手术需要全身麻醉以去除自体脂肪或筋膜来修复漏口,这既具有创伤性又花费高。作者报告了 1 例 25 岁男性垂体瘤患者,该患者在肿瘤内镜切除术后 10 天发生 CSF 鼻漏。作者创新性地在门诊鼻内镜下,依次用浸透聚维酮碘溶液的明胶海绵和碘仿纱布填塞漏口。6 个月的随访显示无 CSF 漏复发。CSF 漏是经蝶窦手术最常见的并发症。作者建议,对于经蝶窦手术后早期较小的脑脊液漏,应首先在门诊鼻内镜下依次用明胶海绵和碘仿纱布填塞漏口,可能达到完全治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b37/11198945/9a6840ba829f/scs-35-1507-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b37/11198945/9a6840ba829f/scs-35-1507-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b37/11198945/9a6840ba829f/scs-35-1507-g001.jpg

相似文献

1
A Novel Nasal Endoscopy-Assisted Method for Sealing Cerebrospinal Fluid Rhinorrhea.一种新型鼻内镜辅助方法用于封闭脑脊液鼻漏。
J Craniofac Surg. 2024;35(5):1507-1508. doi: 10.1097/SCS.0000000000010278. Epub 2024 May 14.
2
Management of intra-operative cerebrospinal fluid leak following endoscopic trans-sphenoidal pituitary surgery.内镜经蝶窦垂体手术后术中脑脊液漏的处理
J Laryngol Otol. 2011 Mar;125(3):311-3. doi: 10.1017/S0022215110002483. Epub 2010 Nov 25.
3
Risk factors impacting intra- and postoperative cerebrospinal fluid rhinorrhea on the endoscopic treatment of pituitary adenomas: A retrospective study of 250 patients.影响内镜治疗垂体腺瘤术中及术后脑脊液鼻漏的风险因素:250 例患者的回顾性研究。
Medicine (Baltimore). 2021 Dec 10;100(49):e27781. doi: 10.1097/MD.0000000000027781.
4
Collagen sponge repair of small cerebrospinal fluid leaks obviates tissue grafts and cerebrospinal fluid diversion after pituitary surgery.胶原海绵修复垂体手术后的小脑脊液漏可避免组织移植和脑脊液分流。
Neurosurgery. 2001 Oct;49(4):885-9; discussion 889-90. doi: 10.1097/00006123-200110000-00020.
5
Prevention of intraoperative cerebrospinal fluid leaks by lumbar cerebrospinal fluid drainage during surgery for pituitary macroadenomas.术中经腰椎引流脑脊液预防垂体大腺瘤手术中脑脊液漏。
J Neurosurg. 2012 Jun;116(6):1299-303. doi: 10.3171/2012.3.JNS112160. Epub 2012 Apr 6.
6
Surgical repair of persisting CSF leaks following standard or extended endoscopic transsphenoidal surgery for pituitary tumor.垂体瘤标准或扩大经蝶窦手术后持续性脑脊液漏的手术修复。
Minim Invasive Neurosurg. 2010 Apr;53(2):55-9. doi: 10.1055/s-0029-1246161. Epub 2010 Jun 8.
7
[Analysis and management of delayed cerebrospinal fluid rhinorrhea after invasive pituitary adenoma surgery].[侵袭性垂体腺瘤手术后迟发性脑脊液鼻漏的分析与处理]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Mar 7;57(3):301-307. doi: 10.3760/cma.j.cn115330-20210520-00285.
8
Low-grade CSF leaks in endoscopic trans-sphenoidal pituitary surgery: efficacy of a simple and fully synthetic repair with a hydrogel sealant.内镜经蝶窦垂体手术中的低级别脑脊液漏:水凝胶密封剂的简单且完全合成修复的疗效。
Acta Neurochir (Wien). 2011 Apr;153(4):815-22. doi: 10.1007/s00701-010-0862-8. Epub 2010 Dec 23.
9
Effectiveness of a Sellar Reconstruction Algorithm in Transsphenoidal Pituitary Surgery: Insights from 490 Cases.鞍区重建算法在经蝶窦垂体手术中的有效性:来自 490 例病例的启示。
World Neurosurg. 2024 Sep;189:e1098-e1108. doi: 10.1016/j.wneu.2024.07.093. Epub 2024 Jul 18.
10
The use of the nasoseptal flap to reduce the rate of post-operative cerebrospinal fluid leaks following endoscopic trans-sphenoidal surgery for pituitary disease.使用鼻中隔瓣降低垂体疾病内镜经蝶窦手术后脑脊液漏的发生率。
Br J Neurosurg. 2013 Dec;27(6):739-41. doi: 10.3109/02688697.2013.795525. Epub 2013 May 22.

本文引用的文献

1
Identification and repair of intraoperative cerebrospinal fluid leaks in endonasal transsphenoidal pituitary surgery: surgical experience in a series of 1002 patients.经鼻蝶窦垂体手术中脑脊液漏的识别与修复:1002 例患者系列手术经验。
J Neurosurg. 2018 Aug;129(2):425-429. doi: 10.3171/2017.4.JNS162451. Epub 2017 Sep 29.
2
Spontaneous and medically induced cerebrospinal fluid leakage in the setting of pituitary adenomas: review of the literature.垂体腺瘤患者并发自发性和医源性脑脊液漏:文献复习。
Neurosurg Focus. 2012 Jun;32(6):E2. doi: 10.3171/2012.4.FOCUS1268.
3
Endoscopic pituitary surgery: a systematic review and meta-analysis.
内镜垂体手术:一项系统评价与荟萃分析
J Neurosurg. 2009 Sep;111(3):545-54. doi: 10.3171/2007.12.17635.
4
Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience.经蝶窦手术的并发症:一项全国性调查结果、文献综述及个人经验
Neurosurgery. 1997 Feb;40(2):225-36; discussion 236-7. doi: 10.1097/00006123-199702000-00001.
5
Cerebrospinal fluid fistula and endoscopic sinus surgery.脑脊液瘘与鼻内镜鼻窦手术
Laryngoscope. 1991 Mar;101(3):250-6. doi: 10.1288/00005537-199103000-00006.