Division of Cardio-Thoracic Surgery, University of Cape Town, Cape Town, South Africa.
Division of Paediatric Anaesthesia, Department of Anesthesia and Perioperative Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
World J Pediatr Congenit Heart Surg. 2024 Nov;15(6):766-773. doi: 10.1177/21501351241256582. Epub 2024 Jul 23.
This study describes the 20-year experience of managing common arterial trunk (CAT) in a low-and-middle-income country and compares the early and medium-term outcomes following the transition from conduit to nonconduit repair at the Red Cross War Memorial Children's Hospital.
Single-center retrospective study of consecutive patients aged less than 18 years who underwent repair of CAT from January 1999 to December 2018 at the Red Cross War Memorial Children's Hospital. Patients with interrupted aortic arch or previous pulmonary artery banding were excluded.
Fifty-four patients had CAT repair during the study period. Thirty-four (63.0%) patients had a conduit repair, and 20 (37.0%) patients had a nonconduit repair. There were two intraoperative deaths. Thirty-day in-hospital mortality was 22.2% (12/54). Overall, in-hospital mortality was 29.6% (16/54). Eight (21.1%) late mortalities were observed. The actuarial survival for the conduit group was 77.5%, 53.4%, and 44.5% at 6, 12, and 27 months, respectively, and the nonconduit group was 58.6% at six months. The overall freedom from reoperation between the conduit group and nonconduit group was 66.2% versus 86.5%, 66.2% versus 76.9%, and 29.8% versus 64.1% at 1, 2, and 8 years, respectively.
The outcomes following the transition to nonconduit repair for CAT in a low- and middle-income setting appear to be encouraging. There was no difference in mortality between conduit and nonconduit repairs, and importantly the results suggest a trend toward lower reintervention rates.
本研究描述了在一个中低收入国家中管理共同动脉干(CAT)的 20 年经验,并比较了在红十字儿童医院从使用移植物修复过渡到非移植物修复后的早期和中期结果。
这是一项单中心回顾性研究,纳入了 1999 年 1 月至 2018 年 12 月期间在红十字儿童医院接受 CAT 修复的年龄小于 18 岁的连续患者。排除中断的主动脉弓或先前肺动脉带环的患者。
在研究期间,有 54 名患者接受了 CAT 修复。34 名(63.0%)患者进行了移植物修复,20 名(37.0%)患者进行了非移植物修复。有 2 例术中死亡。30 天院内死亡率为 22.2%(12/54)。总的来说,院内死亡率为 29.6%(16/54)。观察到 8 例(21.1%)晚期死亡。移植物组的存活率分别为 6、12 和 27 个月时的 77.5%、53.4%和 44.5%,而非移植物组为 6 个月时的 58.6%。在移植物组和非移植物组之间,总体免于再次手术的时间分别为 6 个月时的 66.2%对 86.5%、1 年时的 66.2%对 76.9%、2 年时的 29.8%对 64.1%和 8 年时的 29.8%对 64.1%。
在中低收入环境下从使用移植物修复过渡到非移植物修复 CAT 的结果似乎令人鼓舞。移植物和非移植物修复的死亡率没有差异,重要的是,结果表明再干预率呈下降趋势。