低密度脂蛋白胆固醇作为动脉粥样硬化的致病因素。
LDL cholesterol as a causal agent of atherosclerosis.
作者信息
Pedro-Botet Juan, Climent Elisenda, Benaiges David
机构信息
Unitat de Lípids i Risc Vascular, Hospital del Mar, Barcelona, España; Universitat Autònoma de Barcelona, Barcelona, España.
Unitat de Lípids i Risc Vascular, Hospital del Mar, Barcelona, España; Dpt. MELIS, Universitat Pompeu Fabra, Barcelona, España.
出版信息
Clin Investig Arterioscler. 2024 Dec;36 Suppl 1:S3-S8. doi: 10.1016/j.arteri.2024.07.001. Epub 2024 Jul 22.
Atherosclerosis is a chronic disease that begins in early childhood, and without intervention, progresses throughout life, and inevitably worsens over time, sometimes rapidly. LDL cholesterol, beyond being a cardiovascular risk factor, is a causal agent of atherosclerosis. Without LDL cholesterol there is no atherosclerosis, so the evolution of the disease is modifiable, and even reversible.
动脉粥样硬化是一种始于儿童早期的慢性疾病，若不加以干预，会伴随一生发展，且随着时间推移不可避免地恶化，有时恶化速度还很快。低密度脂蛋白胆固醇不仅是心血管疾病的风险因素，还是动脉粥样硬化的致病因子。没有低密度脂蛋白胆固醇就不会有动脉粥样硬化，因此该疾病的发展是可改变的，甚至是可逆的。
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