女性运动性尿失禁的保守干预措施:系统评价。

Conservative interventions for female exercise-induced urinary incontinence: a systematic review.

机构信息

Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.

School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

BJU Int. 2024 Dec;134(6):906-917. doi: 10.1111/bju.16474. Epub 2024 Jul 23.

Abstract

OBJECTIVE

To systematically review and synthesise what is known about the effectiveness of non-pharmaceutical conservative interventions for the management of urinary incontinence (UI) experienced by women during physical exercise.

METHODS

A systematic search was performed in the following databases in September 2023: the Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Excerpta Medica dataBASE (EMBASE), Scientific Electronic Library Online (SciELO), Latin American and Caribbean Health Sciences Literature (LILACS), and Physiotherapy Evidence Database (PEDro). Studies were deemed eligible if population consisted of females who reported symptoms of UI while participating in physical exercise, and the interventions involved any non-pharmaceutical conservative treatment to manage symptoms during exercise. The primary outcome was severity of UI signs and symptoms. The protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO identifier: CRD42022379138).

RESULTS

Of the 3429 abstracts screened, 19 studies were retained. Pelvic floor muscle training (PFMT) and intravaginal devices were the most commonly investigated modalities. Only two randomised controlled trials (RCTs), both among volleyball players, compared PFMT with no PFM exercise, showing a reduction in pad weight gain after the intervention in the experimental groups only. PFMT with and without biofeedback randomised among soldiers demonstrated a reduction in the frequency of urine leakage episodes in both groups, while supervised and unsupervised PFMT randomised among athletes from different sports showed pad weight gain reduction in the supervised group only. Seven single-arm studies suggested that PFMT alone or combined with other modalities may reduce UI severity in active women based on questionnaires, bladder diaries, and self-reported symptoms. A single-arm and a crossover study found pessary use beneficial in reducing urine leakage based on questionnaires and pad weight gain, respectively. When comparing pessary, tampon, and no intervention, two repeated-measures studies found tampons may reduce leakage more than pessaries in CrossFit exercisers and women performing aerobic exercises. A vaginal sponge also reduced pad weight gain during aerobic exercises. Other modalities (i.e., an intraurethral device, photobiomodulation, and combined therapies) were investigated using case series or single case studies. While all interventions showed some evidence of effectiveness, the results must be interpreted with caution due to methodological limitations and high risk of bias. In particular, despite a high reliance on pad tests as a primary outcome, we identified inconsistencies in how pad tests were administered and interpreted.

CONCLUSION

Only the effectiveness of PFMT to reduce urine leakage during exercise has been evaluated through RCTs, with some evidence of effectiveness. We identified a clear need for higher quality studies, with better reporting on the interventions, and more judicious use and interpretation of outcome measures.

摘要

目的

系统回顾和综合评估针对女性在运动中出现尿失禁(UI)时的非药物保守干预措施的有效性。

方法

2023 年 9 月在以下数据库中进行了系统检索:医学文献分析与检索系统在线(MEDLINE)、护理学及相关健康文献累积索引(CINAHL)、荷兰医学文摘(EMBASE)、科学电子图书馆在线(SciELO)、拉丁美洲和加勒比健康科学文献(LILACS)以及物理治疗证据数据库(PEDro)。如果研究人群为报告在进行体育锻炼时出现 UI 症状的女性,且干预措施涉及任何非药物保守治疗以管理运动期间的症状,则认为该研究符合入选标准。主要结局为 UI 体征和症状的严重程度。该方案已在国际前瞻性系统评价注册库(PROSPERO 标识符:CRD42022379138)中进行了注册。

结果

在 3429 篇摘要中,有 19 项研究被保留。盆底肌训练(PFMT)和阴道内装置是最常被研究的方法。仅有 2 项随机对照试验(RCT),均针对排球运动员,将 PFMT 与不进行 PFM 锻炼进行了比较,仅在实验组中观察到干预后垫重量增加减少。在士兵中进行的有和没有生物反馈的 PFMT 随机对照试验显示,两组的尿失禁发作频率均减少,而在不同运动项目的运动员中进行的监督和非监督 PFMT 随机对照试验仅显示监督组的垫重量增加减少。7 项单臂研究表明,基于问卷、膀胱日记和自我报告的症状,PFMT 单独或联合其他方法可能会降低活跃女性的 UI 严重程度。一项单臂和一项交叉研究发现,在基于问卷和垫重量增加的情况下,使用子宫托可能会减少尿液泄漏。一项阴道海绵也减少了有氧运动中的垫重量增加。其他方法(即尿道内装置、光生物调节和联合治疗)则使用病例系列或单病例研究进行了研究。尽管所有干预措施均显示出一定的有效性,但由于方法学局限性和高偏倚风险,结果必须谨慎解释。特别是,尽管垫测试作为主要结局的高依赖性,但我们发现垫测试的实施和解释存在不一致之处。

结论

只有 RCT 评估了 PFMT 对减少运动时尿液渗漏的有效性,且有一定的有效性证据。我们发现,非常需要进行更高质量的研究,对干预措施进行更好的报告,并更明智地使用和解释结局测量。

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