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利用 DISCOVER 研究中新型内界膜镊的手术干预后术中 OCT 分析视网膜改变。

Analysis of retinal alterations utilizing intraoperative OCT following surgical interventions with novel ILM forceps in the DISCOVER study.

机构信息

The Tony and Leona Campane Center for Excellence in Image-Guided Surgery and Advanced Imaging Research, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave/i32, Cleveland, OH, 44195, USA.

出版信息

Sci Rep. 2024 Jul 23;14(1):16959. doi: 10.1038/s41598-024-67700-8.

DOI:10.1038/s41598-024-67700-8
PMID:39043729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11266399/
Abstract

This study aimed to assess retinal alterations following membrane peeling procedures using novel ILM Forceps with laser ablated surface with the help of intraoperative optical coherence tomography (iOCT). A post-hoc analysis was performed to evaluate iOCT findings in eyes that underwent membrane peeling procedures with the novel ILM Forceps. Pre-peel and post-peel iOCT videos and images were evaluated for each eye to assess for post-peel anatomic alterations. Surgical video/iOCT scan correlation was conducted to evaluate the etiology of anatomic alterations. Thirty-two eyes were included in the analysis. Three eyes (9%) had focal full thickness retinal elevations identified on iOCT following tissue-instrument interaction with the ILM Forceps. Two eyes (6%) had focal inner retinal elevations and one eye (3%) had a full-thickness retinal elevation that were not related to direct tissue-instrument interaction but rather indirect peeling forces. iOCT-identified architectural alterations related to direct-tissue instrument interaction were relatively infrequent (< 10%) with similar frequency to previously reported alterations with other surgical instruments.

摘要

本研究旨在借助术中光学相干断层扫描(iOCT)评估新型 ILM 镊(其镊面经激光烧蚀处理)辅助下的膜剥离手术后视网膜的变化。对接受新型 ILM 镊行膜剥离手术的患者进行了一项回顾性分析,以评估 iOCT 检查结果。对每只眼的术前和术后 iOCT 视频和图像进行评估,以评估术后解剖结构的变化。进行手术视频/iOCT 扫描相关性分析以评估解剖结构变化的病因。共纳入 32 只眼进行分析。术中 ILM 镊与组织相互作用后,iOCT 发现 3 只眼(9%)出现局灶性全层视网膜抬高。2 只眼(6%)出现局灶性内层视网膜抬高,1 只眼(3%)出现全层视网膜抬高,这些改变与直接组织-器械相互作用无关,而是与间接剥除力有关。与直接组织-器械相互作用相关的 iOCT 识别的结构改变相对较少(<10%),与其他手术器械报道的改变频率相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a9/11266399/b0fdbb1faee3/41598_2024_67700_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a9/11266399/10dcf5863404/41598_2024_67700_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a9/11266399/b0fdbb1faee3/41598_2024_67700_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a9/11266399/10dcf5863404/41598_2024_67700_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a9/11266399/b0fdbb1faee3/41598_2024_67700_Fig2_HTML.jpg

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本文引用的文献

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Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3440-3444. doi: 10.1167/iovs.17-21584.
2
Membrane Peeling-Induced Retinal Alterations on Intraoperative OCT in Vitreomacular Interface Disorders From the PIONEER Study.来自先锋研究的玻璃体黄斑界面疾病术中光学相干断层扫描中膜剥离引起的视网膜改变
Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7324-30. doi: 10.1167/iovs.15-17526.
3
Complications of Macular Peeling.
黄斑剥脱的并发症
J Ophthalmol. 2015;2015:467814. doi: 10.1155/2015/467814. Epub 2015 Sep 3.
4
Determination of feasibility and utility of microscope-integrated optical coherence tomography during ophthalmic surgery: the DISCOVER Study RESCAN Results.眼科手术中显微镜集成光学相干断层扫描的可行性和实用性评估:DISCOVER研究RESCAN结果
JAMA Ophthalmol. 2015 Oct;133(10):1124-32. doi: 10.1001/jamaophthalmol.2015.2376.
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INTRAOPERATIVE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING AFTER INTERNAL LIMITING MEMBRANE PEELING IN IDIOPATHIC EPIRETINAL MEMBRANE WITH CONNECTING STRANDS.特发性视网膜前膜伴条索状连接物行内界膜剥除术后的术中光谱域光学相干断层扫描成像
Retina. 2015 Aug;35(8):1622-30. doi: 10.1097/IAE.0000000000000534.
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Factors associated with persistent subfoveal fluid and complete macular hole closure in the PIONEER study.与 PIONEER 研究中持续性中心凹下积液和完全黄斑裂孔闭合相关的因素。
Invest Ophthalmol Vis Sci. 2014 Dec 18;56(2):1141-6. doi: 10.1167/iovs.14-15765.
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The Prospective Intraoperative and Perioperative Ophthalmic ImagiNg with Optical CoherEncE TomogRaphy (PIONEER) Study: 2-year results.前瞻性术中及围手术期光学相干断层扫描眼科成像(PIONEER)研究:2年结果
Am J Ophthalmol. 2014 Nov;158(5):999-1007. doi: 10.1016/j.ajo.2014.07.034. Epub 2014 Jul 29.
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