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一名腹膜透析患者反复发生腹膜炎:一例罕见的地衣芽孢杆菌病例,尽管药敏显示敏感,但万古霉素治疗失败

Repeated Peritonitis in a Peritoneal Dialysis Patient: An Unusual Case of Bacillus licheniformis With Vancomycin Failure Despite Sensitivity.

作者信息

Ali Mohamed Y, Fadul Abdalla, Ali Mohamed O, Mohamed Mohamed Y

机构信息

Internal Medicine, Hamad Medical Corporation, Doha, QAT.

Internal Medicine, University of Missouri-Kansas City, Kansas City, USA.

出版信息

Cureus. 2024 Jul 23;16(7):e65205. doi: 10.7759/cureus.65205. eCollection 2024 Jul.

Abstract

() is an aerobic, gram-positive, spore-forming rod typically found in soil, decaying organic matter, vegetables, and water, and occasionally part of normal gut flora. This report highlights a case of unusual repeated peritonitis caused by , with three episodes occurring over six months, all of which were sensitive to vancomycin yet presented an unclear cause for recurrence. Peritonitis represents a significant cause of mortality, hospitalization, and failure of peritoneal dialysis catheters, leading to forced transitions to hemodialysis. The rarity of  as a pathogen in human infections emphasizes the critical need for precise microbial identification and customized therapeutic strategies.

摘要

()是一种需氧的革兰氏阳性芽孢杆菌,通常存在于土壤、腐烂的有机物、蔬菜和水中,偶尔也是正常肠道菌群的一部分。本报告重点介绍了一例由()引起的罕见复发性腹膜炎病例,在六个月内发生了三次,所有病例对万古霉素敏感,但复发原因不明。腹膜炎是导致死亡、住院和腹膜透析导管功能衰竭的重要原因,会导致被迫转为血液透析。()作为人类感染病原体的罕见性凸显了精确微生物鉴定和定制治疗策略的迫切需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6534/11265539/6d73734c302a/cureus-0016-00000065205-i01.jpg

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