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改变模式:消除——不仅是消除宫颈癌。

Changing the paradigm: Elimination - Not only of cervical cancer.

作者信息

Bornstein Jacob, Sacinti Koray Gorkem, Preti Mario, Billan Salem, Razeghian Hosna, Stockdale Colleen K

机构信息

The Research Institute of Galilee Medical Center, Galilee Medical Center, Nahariya, Israel.

Department of Obstetrics and Gynecology, Azrieli Faculty of Medicine of Bar-Ilan University, Nahariya, Israel.

出版信息

Gynecol Oncol Rep. 2024 Jul 3;54:101445. doi: 10.1016/j.gore.2024.101445. eCollection 2024 Aug.

Abstract

The WHO's initiative to eliminate cervical cancer by 2030 does not address the increasing incidence of vulvar, anal, and oropharyngeal cancers linked to high-risk HPV. Currently, the prevention of these three cancers faces various obstacles, such as a lack of specialized screening programs, well-defined management guidelines, and widespread public awareness. Without any interventions, the incidence of these three cancers will likely rise in the upcoming years, increasingly affecting younger individuals. We recommend expanding the WHO's initiative to include vulvar, anal, and oropharyngeal cancers. This involves developing screening and management protocols similar to those for cervical cancer, implementing gender-neutral HPV vaccination programs, establishing clear referral pathways to specialized centers, promoting public awareness, and providing education to healthcare providers and high-risk individuals.

摘要

世界卫生组织到2030年消除宫颈癌的倡议并未涉及与高危型人乳头瘤病毒(HPV)相关的外阴癌、肛门癌和口咽癌发病率上升的问题。目前,这三种癌症的预防面临各种障碍,如缺乏专门的筛查项目、明确的管理指南以及广泛的公众认知。若无任何干预措施,这三种癌症的发病率在未来几年可能会上升,对年轻人群体的影响也会越来越大。我们建议扩大世界卫生组织的倡议范围,将外阴癌、肛门癌和口咽癌纳入其中。这包括制定与宫颈癌类似的筛查和管理方案,实施不分性别的HPV疫苗接种计划,建立通往专科中心的明确转诊途径,提高公众认知,并为医疗服务提供者和高危个体提供教育。

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本文引用的文献

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Management of Advanced Squamous Cell Carcinoma of the Vulva.晚期外阴鳞状细胞癌的管理
Cancers (Basel). 2021 Dec 30;14(1):167. doi: 10.3390/cancers14010167.
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2020 WHO Classification of Female Genital Tumors.《2020年世界卫生组织女性生殖器官肿瘤分类》
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