对强力蠕动波的批判性分析，以定义强力蠕动性食管疾病。
CRITICAL ANALYSIS OF HYPERCONTRACTILE WAVES VIGOR TO DEFINE HYPERCONTRACTILE ESOPHAGUS DISEASE.
机构信息
Department of Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil.
Rede D'Or São Luiz Hospitals, São Paulo, Brazil.
出版信息
Arq Gastroenterol. 2024 Jul 19;61:e24022. doi: 10.1590/S0004-2803.24612024-022. eCollection 2024.
BACKGROUND
The current definition for hypercontractile esophagus was arbitrarily set at the uppermost range in volunteers for a specific equipment.
OBJECTIVE
This study aims to critically analyze the concept of hypercontractile waves to redefine hypercontractile esophagus parameters.
METHODS
We reviewed 500 unselected and consecutive HRM tests (5000 waves) performed in a water -perfused system.
RESULTS
Mean distal contractility integral (DCI) was 825±1492 (0-42775) mmHg.cm.s, two standard deviations above average = 3810; 95th percentile = 2798 mmHg.cm.s.
CONCLUSION
In healthy volunteers, two standard deviations above average is 4000 mmHg.cm.s, we thus suggest this value to define hypercontractile waves and define hypercontractile esophagus in a water-perfused HRM system.
背景
目前，对于高收缩性食管的定义是在特定设备的志愿者中最高范围内任意设定的。
目的
本研究旨在批判性地分析高收缩波的概念，以重新定义高收缩性食管的参数。
方法
我们回顾了在水灌注系统中进行的 500 次未经选择的连续 HRM 测试（5000 次波）。
结果
平均远端收缩积分（DCI）为 825±1492（0-42775）mmHg.cm.s，平均值以上两个标准差=3810；95%百分位数=2798mmHg.cm.s。
结论
在健康志愿者中，平均值以上两个标准差为 4000mmHg.cm.s，因此我们建议将此值用于定义高收缩波，并在水灌注 HRM 系统中定义高收缩性食管。
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