Wu Pinru, Zeng Jing, Meng Lingkui, Wan Qian
School of Pharmacy, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei, 430071, China.
Chem Commun (Camb). 2024 Aug 13;60(66):8670-8683. doi: 10.1039/d4cc02838d.
Sulfoxides have emerged as pivotal constituents in modern carbohydrate chemistry. As anomeric leaving groups, sulfinyl moieties may occupy positions directly at the anomeric position or at a more remote site. This feature article is focused on the evolution and notable advancements of glycosyl sulfoxide donors in glycosylation reactions. Its objective is to elucidate the obstacles and prospects within this evolving research domain, with the aim of enhancing comprehension and progress in the field of carbohydrate chemistry.
亚砜已成为现代碳水化合物化学中的关键成分。作为异头离去基团，亚磺酰基部分可直接占据异头位置或更偏远的位点。这篇专题文章聚焦于糖基亚砜供体在糖基化反应中的发展历程和显著进展。其目的是阐明这一不断发展的研究领域中的障碍和前景，以期增进对碳水化合物化学领域的理解并推动其进步。
