Pediatric Neurosurgery, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy.
Università Cattolica del Sacro Cuore, Rome, Italy.
Childs Nerv Syst. 2024 Oct;40(10):3173-3178. doi: 10.1007/s00381-024-06545-y. Epub 2024 Jul 24.
Pediatric low-grade gliomas (pLGGs) in the cerebellar vermis present unique challenges due to their intricate anatomical location and potential impact on critical neurological functions. Surgical intervention remains a cornerstone in the management of these tumors, aiming to achieve maximal tumor resection while preserving neurological function. In this review, the authors will discuss anatomical consideration and will explore current surgical techniques and strategies employed in the treatment of cerebellar vermis pLGGs such as the midline and lateral suboccipital approaches, as well as endoscopic-assisted technique. Additionally, we will emphasize the importance of intraoperative neurophysiological monitoring (IONM) in ensuring safe and effective tumor resection. Overall, this review provides insights into the neurosurgical approach of pLGGs in the cerebellar vermis.
儿童小脑蚓部低度胶质瘤（pLGGs）因其复杂的解剖位置和对关键神经功能的潜在影响而带来独特的挑战。手术干预仍然是这些肿瘤治疗的基石，旨在实现最大限度的肿瘤切除，同时保留神经功能。在这篇综述中，作者将讨论解剖学考虑，并探讨目前用于治疗小脑蚓部 pLGGs 的手术技术和策略，如正中及侧方枕下入路，以及内镜辅助技术。此外，我们还将强调术中神经生理监测（IONM）在确保肿瘤安全有效切除中的重要性。总的来说，这篇综述为小脑蚓部 pLGGs 的神经外科治疗方法提供了深入的见解。
