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让我们谈谈性:西班牙放射肿瘤学会GINECOR工作组的共识指南:盆腔放疗后的临床建议。

Let's talk about sex: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology: clinical recommendations after pelvic radiotherapy.

作者信息

Gil Haro Beatriz, Cordoba Largo Sofía, Rodriguez Rodriguez Isabel, Lozano Martin Eva Maria, Couselo Paniagua Maria Luz, Martinez Montesinos Irene, Belinchon Olmeda Belen, Vicente Ruiz Paula, Cerrolaza Pascual Maria, Payano Hernández Stephanyie, Rey-Baltar Oramas Dolores, Martinez Casares Nieves, Barahona Orpinell Manel

机构信息

Department of Radiation Oncology, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.

Radiation Oncology Department, La Paz University Hospital, Madrid, Spain.

出版信息

Clin Transl Oncol. 2025 Feb;27(2):425-438. doi: 10.1007/s12094-024-03562-w. Epub 2024 Jul 24.

DOI:10.1007/s12094-024-03562-w
PMID:39046683
Abstract

PURPOSE

The present consensus statement was developed by the GINECOR working group on behalf of the Spanish Society of Radiation Oncology (SEOR). This document addresses sexual health management in patients with gynaecological cancer after pelvic radiotherapy.

METHODS

A modified two-round online Delphi study was conducted, where GINECOR members were surveyed on the diagnosis, treatment, and follow-up of sexual health problems. An expert panel of radiation oncologists, nurses and a gynaecologist participated in the Delphi study to reach a consensus, applying GRADE criteria to establish the level of agreement.

RESULTS

The consensus recommendations cover both diagnosis and treatment, with an emphasis on patient-reported outcome measures (PROMs). They highlight recommendations such as the systematic assessment of genitourinary, gastrointestinal, and sexual symptoms, and the use of several treatments after radiotherapy. Recommendations include pharmacological options like vaginal lubricants and hormone therapy, and mechanical interventions such as vaginal dilators and vibrators. These suggestions stem from both scientific evidence and clinical expertise.

CONCLUSION

This consensus statement describes a comprehensive, multidisciplinary approach developed to address the sexual needs and enhance the quality of life of patients with gynaecological tumours after pelvic radiotherapy. It offers specific recommendations for managing sexual issues, emphasizing the importance of specialized care and regular assessment. The document underscores the significance of proactive, patient-centered sexual health management in gynaecological cancer patients.

摘要

目的

本共识声明由GINECOR工作组代表西班牙放射肿瘤学会(SEOR)制定。本文档涉及盆腔放疗后妇科癌症患者的性健康管理。

方法

开展了一项经过改进的两轮在线德尔菲研究,对GINECOR成员就性健康问题的诊断、治疗和随访进行了调查。放射肿瘤学家、护士和妇科医生组成的专家小组参与了德尔菲研究以达成共识,应用GRADE标准确定一致程度。

结果

共识建议涵盖诊断和治疗,重点是患者报告的结局指标(PROMs)。它们强调了诸如对泌尿生殖系统、胃肠道和性症状进行系统评估,以及放疗后采用多种治疗方法等建议。建议包括使用阴道润滑剂和激素疗法等药物选择,以及阴道扩张器和振动器等机械干预措施。这些建议源于科学证据和临床专业知识。

结论

本共识声明描述了一种全面的多学科方法,旨在满足盆腔放疗后妇科肿瘤患者的性需求并提高其生活质量。它为管理性问题提供了具体建议,强调了专科护理和定期评估的重要性。该文件强调了对妇科癌症患者进行积极主动、以患者为中心的性健康管理的重要性。

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本文引用的文献

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European Society of Gynaecological Oncology Guidelines for the Management of Patients with Vulvar Cancer - Update 2023.欧洲妇科肿瘤学会外阴癌管理指南 - 2023 年更新版。
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ESTRO/ESGO/SIOPe Guidelines for the management of patients with vaginal cancer.ESTRO/ESGO/SIOP 阴道癌管理患者指南。
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ESGO/ESTRO/ESP Guidelines for the management of patients with cervical cancer - Update 2023.
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Vaginal dilator use more than 9 months is a main prognostic factor for reducing G2‑late vaginal complications in 3D‑vaginal‑cuff brachytherapy (interventional radiotherapy)?阴道扩张器使用超过 9 个月是降低 3D 阴道套囊近距离放疗(介入放疗)中 G2 晚期阴道并发症的主要预测因素吗?
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A longitudinal study of sexual health and quality of life in endometrial carcinoma survivors.子宫内膜癌幸存者的性健康和生活质量的纵向研究。
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Overall Severe Morbidity After Chemo-Radiation Therapy and Magnetic Resonance Imaging-Guided Adaptive Brachytherapy in Locally Advanced Cervical Cancer: Results From the EMBRACE-I Study.局部晚期宫颈癌放化疗后和磁共振成像引导自适应近距离放疗的总体重度并发症:EMBRACE-I 研究结果。
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Support Care Cancer. 2022 Dec 17;31(1):51. doi: 10.1007/s00520-022-07469-6.
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Assessment of Sexual Dysfunction in Cervical Cancer Patients after Different Treatment Modality: A Systematic Review.评估不同治疗方式对宫颈癌患者性功能障碍的影响:系统评价。
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Sexual dysfunction in female cancer survivors: Addressing the problems and the remedies.女性癌症幸存者的性功能障碍:解决问题和补救方法。
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