Radiotherapy, Erasmus MC Cancer Centre, Rotterdam, Please Select, Netherlands
Department of Paediatric Hematology and Oncology, University Children's Hospital, Bonn, Germany.
Int J Gynecol Cancer. 2023 Aug 7;33(8):1185-1202. doi: 10.1136/ijgc-2023-004695.
Primary vaginal malignancies are rare, comprising only 2% of all female genital tract malignancies in adults and 4.5% in children. As part of its mission to improve the quality of care for women with gynecological cancers across Europe, the European Society of Gynaecological Oncology (ESGO) jointly with the European Society for Radiotherapy & Oncology (ESTRO) and the European Society of Pediatric Oncology (SIOPe) developed evidence-based guidelines in order to improve the management of patients with vaginal cancer within a multidisciplinary setting.ESTRO/ESGO/SIOPe nominated practicing clinicians who are involved in the management of vaginal cancer patients and have demonstrated leadership through their expertise in clinical care and research, their national and international engagement and profile as well as dedication to the topics addressed to serve on the expert panel (13 experts across Europe comprising the international development group). To ensure that the statements were evidence based, the current literature was reviewed and critically appraised.In the case of absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the international development group. Prior to publication, the guidelines were reviewed by 112 independent international practitionners in cancer care delivery and patient representatives and their comments and input were incorporated and addressed accordingly.These guidelines cover comprehensively the diagnostic pathways as well as the surgical, radiotherapeutical and systemic management and follow-up of adult patients (including those with rare histological subtypes) and pediatric patients (vaginal rhabdomyosarcoma and germ cell tumours) with vaginal tumours.
原发性阴道恶性肿瘤较为罕见，仅占成人女性生殖道恶性肿瘤的 2%，占儿童生殖道恶性肿瘤的 4.5%。为了提高欧洲妇科癌症患者护理质量，欧洲妇科肿瘤学会（ESGO）与欧洲放射肿瘤学会（ESTRO）和欧洲小儿肿瘤学会（SIOPe）共同制定了基于循证的指南，以便在多学科环境中改善阴道癌患者的管理。ESTRO/ESGO/SIOPe 提名了参与阴道癌患者管理并通过其在临床护理和研究方面的专业知识、国家和国际参与度和专业形象以及对所讨论主题的投入来展示领导力的执业临床医生，担任专家小组（13 名来自欧洲的专家，包括国际发展小组）。为了确保陈述基于证据，对现有文献进行了审查和批判性评估。在缺乏明确科学证据的情况下，判断基于国际发展小组的专业经验和共识。在发布之前，指南由 112 名独立的癌症护理提供者和患者代表进行了审查，他们的意见和建议被纳入并相应处理。这些指南全面涵盖了成人患者（包括罕见组织学亚型患者）和儿科患者（阴道横纹肌肉瘤和生殖细胞肿瘤）阴道肿瘤的诊断途径以及手术、放射治疗和系统管理以及随访。
