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[戒烟药物处方。萨莫拉健康领域的回顾性分析]

[Prescription of drugs for smoking cessation. Retrospective analysis of the health area of Zamora].

作者信息

Majo García Raúl, Fernández-García Daniel, Fernández-Martínez Maria Nélida, Espinosa Villoria Maria Guadalupe, Amaro Rodríguez Laura, Ruiz Cimarras Manuel Angel

机构信息

Centro de Salud de Sanabria, Gerencia Atención Primaria Zamora, Gerencia Asistencia Sanitaria Zamora, Gerencia Regional de Salud Castilla y León (SACYL), Puebla de Sanabria, Zamora, España.

Health Research Nursing Group (GREIS), University of Leon, Department of Nursing and Physiotherapy, University of Leon, León, España.

出版信息

Aten Primaria. 2024 Dec;56(12):103049. doi: 10.1016/j.aprim.2024.103049. Epub 2024 Jul 23.

DOI:10.1016/j.aprim.2024.103049
PMID:39047527
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11318544/
Abstract

OBJECTIVE

To analyze the prescription of drugs to aid smoking cessation and to detect whether there are differences by age or sex.

DESIGN

Retrospective cohort study. SITE: Zamora Health Area.

PARTICIPANTS

Persons with smoking cessation attempts employing drugs funded in the period from 2020 to 2023.

INTERVENTIONS

Request of pharmaceutical consumption of varenicline, bupropion and cytisine to the Pharmacy Information System of the Regional Health Management of Castilla y León.

MAIN MEASUREMENTS

Number of quit attempts per person, treatment drug, number of medication containers per attempt, year, age and sex. Descriptive and statistical analysis using SPSS© v. 20.

RESULTS

2581 people tried to quit smoking with drugs, 2206 made one attempt and 375 made several attempts. Mean age was 50.7 years (95% CI: 50.2-51.1). No significant differences were found for age (P=.71) or sex (P=.74). There was a preference for prescribing varenicline over bupropion and low drug compliance, with only one container of medication being collected in about 50% of cases. A total of 1680 attempts were made to quit using cytisine in 2023, equivalent to 55.4% of the total number of treatment drugs used in the four years. The estimated cumulative incidence rate of drug withdrawal attempts in smokers between 18 and 65 years of age was 11.9%.

CONCLUSIONS

The drug intervention had a low reach and poor compliance with the recommended treatment. It is essential to emphasize patient follow-up and drug adherence.

摘要

目的

分析辅助戒烟药物的处方情况,并检测年龄或性别是否存在差异。

设计

回顾性队列研究。地点:萨莫拉健康区。

参与者

2020年至2023年期间使用资助药物尝试戒烟的人员。

干预措施

向卡斯蒂利亚-莱昂地区卫生管理局的药房信息系统查询伐尼克兰、安非他酮和金雀花碱的药物消费情况。

主要测量指标

每人的戒烟尝试次数、治疗药物、每次尝试的药物容器数量、年份、年龄和性别。使用SPSS© v. 20进行描述性和统计分析。

结果

2581人尝试使用药物戒烟,2206人进行了一次尝试,375人进行了多次尝试。平均年龄为50.7岁(95%置信区间:50.2 - 51.1)。年龄(P = 0.71)或性别(P = 0.74)方面未发现显著差异。与安非他酮相比,更倾向于开具伐尼克兰,但药物依从性较低,约50%的病例仅领取了一个药物容器。2023年共进行了1680次使用金雀花碱戒烟的尝试,相当于四年内使用的治疗药物总数的55.4%。18至65岁吸烟者药物戒断尝试的估计累积发病率为11.9%。

结论

药物干预的覆盖面较低,对推荐治疗的依从性较差。强调患者随访和药物依从性至关重要。

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本文引用的文献

1
Cytisine as a smoking cessation aid: Preliminary observations with a modified therapeutic scheme in real life.烟碱作为戒烟辅助剂:改良治疗方案在现实生活中的初步观察。
Tumori. 2024 Apr;110(2):124-131. doi: 10.1177/03008916231216906. Epub 2023 Dec 27.
2
Cytisine for smoking cessation: A systematic review and meta-analysis.金雀花碱用于戒烟:一项系统评价与荟萃分析。
Drug Alcohol Depend. 2023 Oct 1;251:110936. doi: 10.1016/j.drugalcdep.2023.110936. Epub 2023 Aug 25.
3
Clinical Practice Guideline of Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on Pharmacological Treatment of Tobacco Dependence 2023.
西班牙肺病学和胸外科学会(SEPAR)2023 年药物治疗烟草依赖临床实践指南。
Arch Bronconeumol. 2023 Oct;59(10):651-661. doi: 10.1016/j.arbres.2023.07.024. Epub 2023 Jul 28.
4
Cytisinicline for Smoking Cessation: A Randomized Clinical Trial.盐酸丁丙诺啡用于戒烟:一项随机临床试验。
JAMA. 2023 Jul 11;330(2):152-160. doi: 10.1001/jama.2023.10042.
5
Cytisine Versus Varenicline for Smoking Cessation in a Primary Care Setting: A Randomized Non-inferiority Trial.细胞松弛素与伐伦克林在初级保健环境中戒烟的比较:一项随机非劣效性试验。
Nicotine Tob Res. 2023 Aug 19;25(9):1547-1555. doi: 10.1093/ntr/ntad065.
6
[New drugs financed for smoking cessation].[资助用于戒烟的新药]
Aten Primaria. 2023 Aug;55(8):102647. doi: 10.1016/j.aprim.2023.102647. Epub 2023 May 9.
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