Center for the Study of Drugs Alcohol Smoking and Health, School of Nursing, University of Michigan, 400 N. Ingalls, Ann Arbor, MI 48109, USA.
University of Minnesota, Department of Psychiatry, 2450 Riverside Ave, Minneapolis, MN 55454, USA.
Addict Behav. 2022 May;128:107246. doi: 10.1016/j.addbeh.2022.107246. Epub 2022 Jan 13.
We examined associations of drinking intensity on a given drinking day with acute physical consequences in a sample of U.S. young adult drinkers.
Participants were past 30-day drinkers at modal age 18 in the 2018 12th-grade Monitoring the Future study who were followed up as part of a daily study in 2019 (n = 911). Of these participants, n = 489 reported at least one drinking day. At age 19, they reported their alcohol use and consequences for 14 consecutive days (n = 1051 drinking days). Daily data were used to examine within- and between-person associations of drinking intensity (moderate [1-3 drinks for women, 1-4 drinks for men], binge [4-7/5-9], or high-intensity [8+/10+]) with four acute physical consequences: hangover, nausea, blackout, and passing out.
At least one acute physical consequence was reported on more than half (59.3%) of high-intensity drinking days compared to 40.7% of binge and 4.9% of moderate drinking days. Blackouts and passing out were reported on 17.1% and 9.2% of high-intensity drinking days, respectively. Compared to binge drinking days, high-intensity drinking days were associated with a greater likelihood of any physical consequences (adjusted odds ratio [aOR] = 4.64; 95% confidence interval [CI] = 2.00,10.75), a greater number of consequences (adjusted incident rate ratio [aIRR = 1.99; 95% CI = 1.16,3.42), and a greater likelihood of hangover (aOR = 3.72; 95% CI = 1.58,8.74). Acute physical consequences were also more likely on high-intensity and binge drinking days versus moderate drinking days.
High-intensity drinking days were associated with a distinctly greater risk for acute physical consequences than binge or moderate drinking days.
我们在一个美国年轻成年饮酒者样本中，研究了某一天饮酒强度与急性身体后果之间的关联。
2018 年 12 年级监测未来研究中，在过去 30 天内饮酒的参与者年龄为 18 岁，是模式年龄，他们作为 2019 年一项日常研究的一部分进行了随访（n=911）。在这些参与者中，n=489 报告了至少一天的饮酒。在 19 岁时，他们报告了 14 天连续的饮酒和后果（n=1051 个饮酒日）。使用每日数据来检验饮酒强度（女性 1-3 杯，男性 1-4 杯为中度，4-7/5-9 杯为 binge，8+/10+为高强度）与四种急性身体后果（宿醉、恶心、断片、昏厥）之间的个体内和个体间关联。
在高强度饮酒日，报告至少一种急性身体后果的比例超过一半（59.3%）， binge 饮酒日为 40.7%，中度饮酒日为 4.9%。断片和昏厥分别报告在 17.1%和 9.2%的高强度饮酒日。与 binge 饮酒日相比，高强度饮酒日更有可能发生任何身体后果（调整后的优势比[aOR] = 4.64；95%置信区间[CI] = 2.00,10.75），发生更多的后果（调整后的发生率比[aIRR] = 1.99；95%置信区间[CI] = 1.16,3.42），以及更有可能出现宿醉（aOR] = 3.72；95%置信区间[CI] = 1.58,8.74）。与中度饮酒日相比，高强度和 binge 饮酒日发生急性身体后果的可能性也更大。
与 binge 或中度饮酒日相比，高强度饮酒日与急性身体后果的风险明显更高。
