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儿童胎儿弯曲杆菌感染

Campylobacter fetus infections in children.

作者信息

Torphy D E, Bond W W

出版信息

Pediatrics. 1979 Dec;64(6):898-903.

PMID:390487
Abstract

There has been a gradual accumulation of reported Campylobacter fetus human infections since the first description in 1947. The taxonomy of these fastidious and morphologically confusing organisms has been recently revised and, in the past few years, through the use of selective culture medium for stool isolation C fetus has been implicated as a frequent paghogen in children. There are three relatively distinct patterns of human C fetus infection. The first, most frequent, pattern of disease is enteritis which is usually uncomplicated and due to C fetus subsp jejuni. A second form of disease consists of focal infections, often associated with vasculitis and/or chronic bacteremia. These infections, due to C fetus subsp intestinalis, are seen most often in older, debilitated, or chronically ill men. The third pattern, perinatal infections causing abortion, prematurity, and neonatal meningitis, is the least frequent, but these infections are usually fetal to the fetus or infant and are also due to C fetus subsp intestinalis.

摘要

自1947年首次描述以来,已报告的胎儿弯曲杆菌人类感染病例逐渐增多。这些苛求且形态易混淆的微生物的分类学最近已被修订,并且在过去几年中,通过使用用于粪便分离的选择性培养基,胎儿弯曲杆菌已被认为是儿童中常见的病原体。人类胎儿弯曲杆菌感染有三种相对不同的模式。第一种也是最常见的疾病模式是肠炎,通常不复杂,由胎儿弯曲杆菌空肠亚种引起。第二种疾病形式包括局灶性感染,通常与血管炎和/或慢性菌血症有关。这些感染由胎儿弯曲杆菌肠道亚种引起,最常见于老年、体弱或慢性病男性。第三种模式是围产期感染导致流产、早产和新生儿脑膜炎,这种情况最少见,但这些感染通常对胎儿或婴儿是致命的,也由胎儿弯曲杆菌肠道亚种引起。

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