Rennie R P, Strong D, Taylor D E, Salama S M, Davidson C, Tabor H
Department of Medical Microbiology, University of Alberta, Edmonton, Canada.
J Clin Microbiol. 1994 Mar;32(3):721-4. doi: 10.1128/jcm.32.3.721-724.1994.
Following a case of Campylobacter fetus sepsis and meningitis in a 4-month-old female member of a Hutterite colony, an epidemiological investigation revealed at least 18 cases of diarrhea in other members of the colony. C. fetus was isolated from 7 of 15 fecal samples submitted from affected persons. A case control study suggested that persons who worked in the abattoir were 2.03 times more likely to have had diarrhea, but none of the risk factors studied were significant. The epicurve of the outbreak was inconclusive as to the likely mode of spread of C. fetus. All of the C. fetus strains isolated from the blood of the infant and from the fecal samples were the same by biochemical and antibiotic susceptibility tests. Pulsed-field gel electrophoresis showed that all isolates produced identical restriction endonuclease patterns and differed from other nonepidemiologically related strains of C. fetus.
在一名哈特教派聚居地的4个月大女婴感染胎儿弯曲杆菌败血症和脑膜炎之后,一项流行病学调查发现该聚居地其他成员中至少有18例腹泻病例。从15份受影响人员提交的粪便样本中,有7份分离出了胎儿弯曲杆菌。一项病例对照研究表明,在屠宰场工作的人患腹泻的可能性高出2.03倍,但所研究的危险因素均无统计学意义。此次疫情的流行曲线对于胎儿弯曲杆菌可能的传播方式并无定论。通过生化和抗生素敏感性试验,从婴儿血液和粪便样本中分离出的所有胎儿弯曲杆菌菌株均相同。脉冲场凝胶电泳显示,所有分离株产生相同的限制性内切酶图谱,与其他非流行病学相关的胎儿弯曲杆菌菌株不同。