Khan Raza, Khachemoune Amor
University of Oklahoma Health Sciences Center, College of Medicine, Oklahoma City, Oklahoma, USA.
Departments of Dermatology, SUNY Downstate, New York, USA.
Indian Dermatol Online J. 2024 Jun 10;15(4):584-592. doi: 10.4103/idoj.idoj_756_23. eCollection 2024 Jul-Aug.
Morphea, an autoimmune progressive disorder, can significantly impact patient well-being, yet therapeutic options, though expanding, exhibit limited efficacy. A persistent challenge in disease management revolves around monitoring disease activity and gauging treatment effectiveness. To address this, various clinical assessment tools have been devised, each with its inherent limitations. The realm of imaging in morphea has undergone noteworthy expansion, with ultrasonography (US) emerging as an efficacious and cost-effective avenue for quantifying disease activity and evaluating therapeutic outcomes. However, the evidential support for its application remains equivocal. Our aim was to explore and analyze the existing evidence concerning the utility of ultrasound in the management of morphea.
We conducted a comprehensive literature review using PubMed Medline to assess evidence concerning US utility in morphea management.
Sixteen total studies were included in our review.
Although the studies presented carry their own limitations, cumulative findings indicate the potential of ultrasound, particularly when coupled with Doppler, in facilitating staging, assessing disease activity, and longitudinal assessment of therapeutic efficacy in patients with morphea.
硬斑病是一种自身免疫性进行性疾病，会对患者的健康产生重大影响。尽管治疗选择在不断增加，但其疗效仍然有限。疾病管理中的一个持续挑战是监测疾病活动和评估治疗效果。为了解决这个问题，已经设计了各种临床评估工具，但每种工具都有其固有的局限性。硬斑病的影像学领域有了显著扩展，超声检查（US）已成为量化疾病活动和评估治疗结果的有效且具有成本效益的途径。然而，其应用的证据支持仍然不明确。我们的目的是探索和分析关于超声在硬斑病管理中的效用的现有证据。
我们使用PubMed Medline进行了全面的文献综述，以评估关于超声在硬斑病管理中的效用的证据。
我们的综述共纳入了16项研究。
尽管所呈现的研究有其自身的局限性，但累积的研究结果表明超声，特别是与多普勒结合使用时，在硬斑病患者的分期、评估疾病活动和治疗疗效的纵向评估方面具有潜力。
