This is a review of the chemistry and structure of synthetic, mineral, and biologic hydroxyapatites. Bone apatite has a large, reactive specific-surface and is characterized by its crystal imperfection and non-stoichiometry. Precipitated and bone hydroxyapatites are in the submicroscopic size range where their solubility decreases rapidly with a small increment of crystal growth. A discussion is given of the various mechanisms proposed for tissue mineralization. The body seems to contain a number of nucleating and inhibiting mechanisms which seem to work in concert, possibly providing redundant pathways to the mineralization of tissue.
这是一篇关于合成羟基磷灰石、矿物羟基磷灰石和生物羟基磷灰石的化学与结构的综述。骨磷灰石具有大的、具有反应活性的比表面积，其特征在于晶体缺陷和非化学计量比。沉淀羟基磷灰石和骨羟基磷灰石处于亚微观尺寸范围，在该范围内，随着晶体生长的少量增加，它们的溶解度迅速降低。文中讨论了提出的各种组织矿化机制。人体似乎包含许多成核和抑制机制，这些机制似乎协同作用，可能为组织矿化提供了冗余途径。
