Wellness Data, LLC, Washington, DC, USA.
J Int Assoc Provid AIDS Care. 2024 Jan-Dec;23:23259582241245228. doi: 10.1177/23259582241245228.
The primary goal of medical care during the pre-antiretroviral therapy (ART) era was to keep persons living with human immunodeficiency virus (HIV) alive, whereas since the advent of ART, the treatment objective has shifted to decreasing viral loads and infectiousness while increasing CD4+ T-cell counts and longevity. The health crisis, however, is in preventing and managing multimorbidity (ie, type 2 diabetes), which develops at a more accelerated or accentuated pace among aging persons living with HIV. Relative to the general population and age-matched uninfected adults, it may be more difficult for aging HIV-positive persons who also suffer from multimorbidity to improve negative lifestyle factors to the extent that their behaviors could support the prevention and management of diseases. With recommendations and a viable solution, this article explores the impact of negative lifestyle factors (ie, poor mental health, suboptimal nutrition, physical inactivity, alcohol use) on the health of aging individuals living with HIV.
在抗逆转录病毒疗法（ART）时代之前，医疗保健的主要目标是维持人类免疫缺陷病毒（HIV）感染者的生命，而自从 ART 出现以来，治疗目标已经转变为降低病毒载量和传染性，同时增加 CD4+T 细胞计数和延长寿命。然而，健康危机在于预防和管理多种疾病（即 2 型糖尿病），在 HIV 感染者中，这些疾病在老年人中发展得更快或更严重。与一般人群和年龄匹配的未感染者相比，患有多种疾病的老年 HIV 阳性者可能更难以改善不良的生活方式因素，使其行为能够支持疾病的预防和管理。本文探讨了消极的生活方式因素（即心理健康状况不佳、营养状况不佳、身体活动不足、饮酒）对患有多种疾病的老年 HIV 感染者健康的影响，并提出了相关建议和可行的解决方案。
