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腹部手术后带载体纤维蛋白密封剂(TachoSil)的长期持久性:长达十年的随访研究。

Long-term persistence of carrier-bound fibrin sealant (TachoSil) following abdominal surgery: a decade-long follow-up study.

机构信息

Department of Surgery, University of Catania, Via Santa Sofia, 78, 95123, Catania, Italy.

Department of Surgical Sciences and Advanced Technologies "G.F. Ingrassia", Cannizzaro Hospital, General Surgery, University of Catania, Via Messina, 829, Catania, Italy.

出版信息

Updates Surg. 2024 Sep;76(5):2081-2085. doi: 10.1007/s13304-024-01952-x. Epub 2024 Jul 25.

Abstract

This study analyzed the long-term effects of carrier-bound fibrin sealant (CBFS) following abdominal surgery by tracking patients for years post-application. From 2006 to 2022, patients who underwent this procedure were contacted via telephone. Those who died due to underlying diseases, natural causes, or refused the check-up were excluded from the study. After 11 years of follow-up, CBFS was observed in different forms on computed tomography scans in four patients. Our findings indicate that CBFS can persist for years after the procedure. While we cannot confirm any secondary effects, it appears that CBFS sponges are not resorbed within 12 weeks and can remain for many years post-implantation.

摘要

本研究通过对接受腹部手术后多年的患者进行随访,分析了载体结合纤维蛋白密封剂(CBFS)的长期效果。2006 年至 2022 年,通过电话联系接受该手术的患者。由于潜在疾病、自然原因或拒绝检查而死亡的患者被排除在研究之外。在 11 年的随访后,在 4 名患者的计算机断层扫描中观察到 CBFS 以不同形式存在。我们的研究结果表明,在手术后多年 CBFS 仍可存在。虽然我们不能确认任何继发性影响,但 CBFS 海绵似乎不会在 12 周内被吸收,并且在植入后可以存在多年。

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