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纤维蛋白密封剂:速即纱®在腹部手术中的临床应用。急诊外科六年经验及文献综述。

Fibrin sealant agents: clinical application of TachoSil® in abdominal surgery. Six years experience in an emergency surgery department and review of the literature.

作者信息

Fontana T, Silvestri V, Falco N, Venturelli P, Licari L, De Marco P, Gulotta E, Gulotta L, Cocorullo G

出版信息

G Chir. 2018 Sep-Oct;34(5):326-330.

Abstract

BACKGROUND

The success of every surgical procedure depends on an appropriate hemostatis. Topical haemostatic agents, like fibrin sealants, are an option for providing haemostasis and may be particularly useful for complex injuries.

AIM

The aim of the study is to evaluate the use of TachoSil® in abdominal surgery and its benefits to prevent bleedings, and to establish its fields of use.

METHODS

A retrospective observational study was performed on 308 patients underwent to emergency surgery with TachoSil®'s application into our department between January 2012 and March 2018.

RESULTS

After the application of the hemostatic device there have been no haemorrhagic complications that have needed a second surgical intervention. Most frequently use of TachoSil® was in the gallbladder bed after cholecystectomy for an acute cholecystitis.

CONCLUSIONS

Our experience, supported by other reports in the literature, suggests the use of TachoSil® may provide an effective option in helping to control bleedings.

摘要

背景

每一台外科手术的成功都依赖于适当的止血措施。局部止血剂,如纤维蛋白密封剂,是实现止血的一种选择,对于复杂损伤可能特别有用。

目的

本研究旨在评估速即纱®在腹部手术中的应用及其预防出血的益处,并确定其应用领域。

方法

对2012年1月至2018年3月间在我科接受急诊手术并应用速即纱®的308例患者进行了一项回顾性观察研究。

结果

应用止血装置后,未出现需要二次手术干预的出血并发症。速即纱®最常用于急性胆囊炎胆囊切除术后的胆囊床。

结论

我们的经验,得到文献中其他报告的支持,表明使用速即纱®可能为帮助控制出血提供一种有效的选择。

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