Birnholz J C
Early Hum Dev. 1985 Nov;12(2):199-209. doi: 10.1016/0378-3782(85)90182-3.
The fetal eye is studied ultrasonically during the second and third trimesters with a large aperture, dynamically focused imaging system. The globe, lens, iris, pupil, and cornea can be resolved separately, and extraocular structures including muscles, retro-orbital fat, and optic nerve may be visualized. The hyaloid artery is seen before 20 weeks and regresses by 25 weeks gestational age. Average vitreous diameter in 157 normal cases exhibits acclerations between 12 and 20 weeks, between 28 and 32 weeks, and near term with decelerations intervening. Associations between limited ocular growth and delayed cerebral development are reaffirmed.
在妊娠中期和晚期,使用大孔径、动态聚焦成像系统对胎儿眼睛进行超声检查。眼球、晶状体、虹膜、瞳孔和角膜能够被分别分辨出来,包括肌肉、眶后脂肪和视神经在内的眼外结构也可以被观察到。玻璃体动脉在孕20周前可见,在孕25周时退化。157例正常病例的玻璃体平均直径在孕12至20周、28至32周以及接近足月时呈现加速增长,中间有减速期。再次证实了有限的眼部生长与脑发育延迟之间的关联。