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mTOR Signaling and Human Physiology Relevant to Kidney Disease.

作者信息

Yamaguchi Junna, Canaud Guillaume

机构信息

Université Paris Cité, Paris, France; Unité de Médecine Translationnelle et Thérapies Ciblées, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; and INSERM U1151, Institut Necker-Enfants Malades, Paris, France.

出版信息

J Am Soc Nephrol. 2024 Jul 25;35(9):1139-40. doi: 10.1681/ASN.0000000000000450.

DOI:10.1681/ASN.0000000000000450
PMID:39053582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11387027/
Abstract
摘要

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本文引用的文献

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PIK3CA inhibition in models of proliferative glomerulonephritis and lupus nephritis.在增殖性肾小球肾炎和狼疮性肾炎模型中抑制磷脂酰肌醇-3激酶催化亚基α（PIK3CA）
J Clin Invest. 2024 Jun 6;134(15):e176402. doi: 10.1172/JCI176402.
2
Dicer-Mediated mTORC1 Signaling and Parathyroid Gland Integrity and Function.Dicer介导的mTORC1信号传导与甲状旁腺的完整性和功能
J Am Soc Nephrol. 2024 May 31;35(9):1183-97. doi: 10.1681/ASN.0000000000000394.
3
mTORc2 in Distal Convoluted Tubule and Renal K + Excretion during High Dietary K + Intake.高钾饮食期间远端肾小管中的mTORc2与肾脏钾排泄
J Am Soc Nephrol. 2024 May 24;35(9):1149-63. doi: 10.1681/ASN.0000000000000406.
4
mTOR signaling in renal ion transport.肾脏离子转运中的mTOR信号传导。
Acta Physiol (Oxf). 2023 May;238(1):e13960. doi: 10.1111/apha.13960. Epub 2023 Apr 13.
5
Physiology and Pathophysiology of Potassium Homeostasis: Core Curriculum 2019.钾稳态的生理学和病理生理学：2019 年核心课程。
Am J Kidney Dis. 2019 Nov;74(5):682-695. doi: 10.1053/j.ajkd.2019.03.427. Epub 2019 Jun 19.
6
Roles of mTOR complexes in the kidney: implications for renal disease and transplantation.mTOR 复合物在肾脏中的作用：对肾脏疾病和移植的影响。
Nat Rev Nephrol. 2016 Oct;12(10):587-609. doi: 10.1038/nrneph.2016.108. Epub 2016 Aug 1.
7
mTORC2 critically regulates renal potassium handling.哺乳动物雷帕霉素靶蛋白复合物2（mTORC2）对肾脏钾离子处理起着关键调节作用。
J Clin Invest. 2016 May 2;126(5):1773-82. doi: 10.1172/JCI80304. Epub 2016 Apr 4.
8
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.AKT2 对于在慢性肾脏病期间维持足细胞的存活和功能至关重要。
Nat Med. 2013 Oct;19(10):1288-96. doi: 10.1038/nm.3313. Epub 2013 Sep 22.
9
Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression.雷帕霉素诱导的低磷血症和胰岛素抵抗与 mTORC2 激活和 Klotho 表达有关。
Am J Transplant. 2011 Aug;11(8):1656-64. doi: 10.1111/j.1600-6143.2011.03590.x. Epub 2011 Jun 14.
10
TOR signaling in growth and metabolism.生长与代谢中的TOR信号传导
Cell. 2006 Feb 10;124(3):471-84. doi: 10.1016/j.cell.2006.01.016.