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贫血和慢性鼻炎对韩国成年人听力损失的联合影响:一项全国性观察研究。

Combined effect of anemia and chronic rhinitis on hearing loss in Korean adults: a nationwide observational study.

机构信息

Departement of Preventive Medicine and Public Health, Ajou University School of Medicine, Suwon, Korea.

Graduate School of Public Health, Ajou University, Suwon, Korea.

出版信息

Epidemiol Health. 2024;46:e2024063. doi: 10.4178/epih.e2024063. Epub 2024 Jul 15.

Abstract

OBJECTIVES

Studies have suggested an association between hearing loss and anemia. Hearing loss has also been linked to rhinitis, which is characterized by inflammation of the nasal mucous membranes and sinus mucosa. Few studies have concurrently explored the relationships between hearing loss, anemia, and rhinitis. This study was conducted to investigate the association between hearing loss and anemia and to further analyze the potential role of rhinitis in this relationship.

METHODS

Data were collected from the 2020 Korea National Health and Nutrition Examination Survey. Hearing loss was measured with an audiometer in a soundproof booth and was defined as at least moderate impairment (as indicated by a pure-tone average of ≥41 dB in the better-hearing ear). The association between hearing loss and anemia was analyzed using multivariable logistic regression. The combined effect of anemia and rhinitis on hearing loss was assessed with an interaction term.

RESULTS

Among the 2,772 participants, 477 (17.2%) exhibited hearing loss. Participants with anemia were more likely to experience hearing loss than those without anemia (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.07 to 2.33). Furthermore, the odds of hearing loss were greater in participants with both anemia and rhinitis (OR, 3.79; 95% CI, 1.93 to 7.43) relative to those without either condition.

CONCLUSIONS

Anemia was associated with hearing loss in individuals aged 40 years and older. Based on the analysis of combined effects, participants with anemia and chronic rhinitis were more likely to experience hearing loss than individuals without these conditions.

摘要

目的

已有研究表明听力损失与贫血之间存在关联。此外,听力损失还与以鼻腔黏膜和鼻窦黏膜炎症为特征的鼻炎有关。很少有研究同时探讨听力损失、贫血和鼻炎之间的关系。本研究旨在调查听力损失与贫血之间的关联,并进一步分析鼻炎在这种关系中的潜在作用。

方法

数据来自 2020 年韩国国家健康与营养调查。在隔音室内使用听力计测量听力损失,将至少中度听力障碍(较好耳的纯音平均听力≥41dB)定义为听力损失。使用多变量逻辑回归分析听力损失与贫血之间的关系。使用交互项评估贫血和鼻炎对听力损失的综合影响。

结果

在 2772 名参与者中,有 477 名(17.2%)存在听力损失。与无贫血者相比,贫血者更有可能出现听力损失(比值比[OR],1.58;95%置信区间[CI],1.07 至 2.33)。此外,与既无贫血又无鼻炎的参与者相比,同时患有贫血和鼻炎的参与者发生听力损失的几率更高(OR,3.79;95%CI,1.93 至 7.43)。

结论

40 岁及以上人群中,贫血与听力损失相关。基于联合效应的分析,患有贫血和慢性鼻炎的参与者发生听力损失的可能性高于不具有这些病症的参与者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db67/11576524/3130e19f1e47/epih-46-e2024063f1.jpg

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