Haaksma Mark Evert, van der Bie Sjoerd, van Soest Ellert J, Vermin Ben, Goeijenbier Marco
Department of Intensive Care Medicine, Spaarne Gasthuis Hospital- Hoofddorp, Rotterdam, The Netherlands.
Department of Gastro-enterology, Spaarne Gasthuis Hospital- Hoofddorp, Rotterdam, The Netherlands.
Saudi J Med Med Sci. 2024 Jul-Sep;12(3):266-269. doi: 10.4103/sjmms.sjmms_629_23. Epub 2024 Jun 20.
Sarcoidosis is a disease of unknown etiology, characterized by noncaseating granulomas. Generally, the condition primarily manifests in the lungs. Extrapulmonary involvement is common, but localization in the gastrointestinal system is rare. Here, we present the case of a 37-year-old male who became increasingly hemodynamically unstable during the diagnostic workup for sarcoidosis due to acute variceal bleeding. The underlying mechanism was later attributed to portal hypertension caused by hepatic involvement of the disease. This case demonstrates the importance of considering variceal hemorrhage as a rare but life-threatening complication of gastrointestinal localization of sarcoidosis.
结节病是一种病因不明的疾病,其特征为非干酪样肉芽肿。一般来说,该病主要表现在肺部。肺外受累很常见,但在胃肠道系统定位却很罕见。在此,我们报告一例37岁男性病例,该患者在结节病诊断检查过程中因急性静脉曲张出血而血流动力学稳定性日益下降。其潜在机制后来归因于疾病肝脏受累导致的门静脉高压。该病例表明,应将静脉曲张出血视为结节病胃肠道定位的一种罕见但危及生命的并发症,这一点很重要。