Beegle Scott H, Barba Kerry, Gobunsuy Romel, Judson Marc A
Division of Pulmonary and Critical Care Medicine, Albany Medical College, Albany, NY 12208, USA.
Drug Des Devel Ther. 2013 Apr 12;7:325-38. doi: 10.2147/DDDT.S31064. Print 2013.
The treatment of sarcoidosis is not standardized. Because sarcoidosis may never cause significant symptoms or organ dysfunction, treatment is not mandatory. When treatment is indicated, oral corticosteroids are usually recommended because they are highly likely to be effective in a relative short period of time. However, because sarcoidosis is often a chronic condition, long-term treatment with corticosteroids may cause significant toxicity. Therefore, corticosteroid sparing agents are often indicated in patients requiring chronic therapy. This review outlines the indications for treatment, corticosteroid treatment, and corticosteroid sparing treatments for sarcoidosis.
结节病的治疗并不规范。由于结节病可能永远不会引起明显症状或器官功能障碍,因此并非必须进行治疗。当需要治疗时,通常推荐口服糖皮质激素,因为它们很可能在相对较短的时间内有效。然而,由于结节病往往是一种慢性疾病,长期使用糖皮质激素治疗可能会导致严重的毒性。因此,对于需要长期治疗的患者,通常会使用糖皮质激素节省剂。这篇综述概述了结节病的治疗指征、糖皮质激素治疗以及糖皮质激素节省治疗。