Fedkov Dmytro, Peine Christine, Khalil Abdullah, Lang Felix
Department of Internal Medicine No. 3, Bogomolets National Medical University, Kyiv, Ukraine.
Medical Center Medical Clinic Blagomed LLC, Kyiv, Ukraine.
Reumatologia. 2024;62(3):161-168. doi: 10.5114/reum/190272. Epub 2024 Jul 12.
Recently, diet has received considerable attention as an important factor in inflammatory arthritis. The objective of this study was to evaluate disease activity and fatigue in patients with rheumatoid arthritis and spondyloarthritis (including psoriatic arthritis) depending on their dietary preferences.
We retrospectively evaluated data of 774 patients collected by the Mida Rheuma App from January 2022 to December 2022. We assessed demographic parameters, major dietary patterns, and food groups (dairy products, fruits, vegetables, processed meat, meat, oily fish, white fish, and sugar) by each patient's consumption intensity. Disease activity was measured by Routine Assessment of Patient Index Data 3 (RAPID3), Patient's Global Assessment of Disease Activity (PtGADA), and Patient's Global Assessment of Pain Intensity (PPAIN). Fatigue was assessed by the Brief Fatigue Inventory (BFI). Depending on the food group, patients were divided into a high-consumption group (HCG; consuming the product 0-2 times per day/per week) and a lowconsumption group (LCG; consuming the product 3 and more times per day/per week). Patients on a specific diet which they followed before inclusion in the analysis were compared with the "eat all group" (EAG).
The Mediterranean diet group had significantly lower ( < 0.05) RAPID3, PtGADA, and PPAIN (by 9.22%, 8.98%, and 14.3%, respectively), compared with the EAG. In the processed meat HCG, RAPID3, PtGADA, PPAIN, and BFI were significantly higher (14.5%, 18.3%, 16.1%, and 11.8%, < 0.05) vs. the LCG. The PtGADA, PPAIN, and RAPID3 were significantly lower ( < 0.05) in the oily fish HCG vs. the LCG (18.9%, 18.1%, and 10.6%).
Our study results suggest that Mediterranean diet and oily fish have a potentially positive impact on patient-reported disease activity and fatigue in patients with inflammatory arthritis. In contrast, processed meat consumption has a negative effect.
最近，饮食作为炎症性关节炎的一个重要因素受到了广泛关注。本研究的目的是根据类风湿关节炎和脊柱关节炎（包括银屑病关节炎）患者的饮食偏好评估其疾病活动度和疲劳程度。
我们回顾性评估了2022年1月至2022年12月期间通过Mida Rheuma应用程序收集的774例患者的数据。我们根据每位患者的消费强度评估了人口统计学参数、主要饮食模式和食物类别（乳制品、水果、蔬菜、加工肉类、肉类、油性鱼类、白鱼和糖）。通过患者指数数据3的常规评估（RAPID3）、患者对疾病活动度的整体评估（PtGADA）和患者对疼痛强度的整体评估（PPAIN）来测量疾病活动度。通过简短疲劳量表（BFI）评估疲劳程度。根据食物类别，患者被分为高消费组（HCG；每天/每周食用该产品0 - 2次）和低消费组（LCG；每天/每周食用该产品3次及以上）。将纳入分析前遵循特定饮食的患者与“全食组”（EAG）进行比较。
与EAG相比，地中海饮食组的RAPID3、PtGADA和PPAIN显著更低（<0.05）（分别降低9.22%、8.98%和14.3%）。在加工肉类HCG组中，与LCG组相比，RAPID3、PtGADA、PPAIN和BFI显著更高（分别高出14.5%、18.3%、16.1%和11.8%，<0.05）。与LCG组相比，油性鱼类HCG组的PtGADA、PPAIN和RAPID3显著更低（<0.05）（分别降低18.9%、18.1%和10.6%）。
我们的研究结果表明，地中海饮食和油性鱼类对炎症性关节炎患者报告的疾病活动度和疲劳可能有积极影响。相比之下，食用加工肉类有负面影响。
