Inan Mustafa Ilker, Balaban Yasemin Akgul, Yesillik Sait, Kartal Ozgur
Ankara Gulhane Training and Research Hospital, Division of Immunology and Allergic Diseases, Ankara, Turkiye.
Allergol Select. 2024 Jul 4;8:233-237. doi: 10.5414/ALX02502E. eCollection 2024.
Anaphylaxis is a severe and life-threatening systemic hypersensitivity reaction. The most frequently encountered causes are foods, drugs, and bee venom, but anaphylaxis may also occur idiopathically. Paradoxical vocal cord movement (PVCM), is a cause of upper airway obstruction due to abnormal adduction of vocal cords during inspiration and, to some degree on expiration. It may be misdiagnosed as asthma or anaphylaxis, and there may be delays in diagnosis.
We present a 20-year-old male patient with coexistence of urticaria and stridor findings who was evaluated and treated as having idiopathic anaphylaxis but then was diagnosed with PVCM after recurrence of stridor attacks.
It is useful to bear the diagnosis of PVCM in mind in patients with recurrent and unexplained stridor or in patients with stridor that does not improve despite treatment for another diagnosis such as anaphylaxis. This way, administration of epinephrine, high-dose corticosteroids and interventions such as intubation or tracheostomy can be avoided.
过敏反应是一种严重的、危及生命的全身性超敏反应。最常见的病因是食物、药物和蜂毒,但过敏反应也可能特发性发生。矛盾性声带运动(PVCM)是吸气时声带异常内收导致上气道阻塞的原因,在某种程度上呼气时也会出现。它可能被误诊为哮喘或过敏反应,并且可能存在诊断延迟。
我们介绍一名20岁男性患者,该患者同时存在荨麻疹和喘鸣症状,最初被评估并当作特发性过敏反应进行治疗,但在喘鸣发作复发后被诊断为PVCM。
对于反复出现不明原因喘鸣的患者或尽管接受了诸如过敏反应等其他诊断的治疗但喘鸣仍未改善的患者,应考虑PVCM的诊断。这样可以避免使用肾上腺素、大剂量皮质类固醇以及插管或气管切开等干预措施。