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结节性后部巩膜炎酷似黑瘤性脉络膜黑色素瘤:诊断困境。

Nodular posterior scleritis mimicking melanotic choroidal melanoma: A diagnostic dilemma.

机构信息

Department of Vitreo-Retina, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.

Department of Oculoplasty, Cataract and Refractive Surgery, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.

出版信息

Eur J Ophthalmol. 2024 Nov;34(6):NP15-NP18. doi: 10.1177/11206721241266698. Epub 2024 Jul 26.

Abstract

PURPOSE

To report a case of atypical nodular posterior scleritis mimicking as a melanotic choroidal melanoma.

METHODS

Descriptive case report.

RESULTS

A 38-year-old female presented with sudden onset diminution of vision, severe pain and redness in her right eye. She was diagnosed to have choroidal melanoma in her left eye one year ago and underwent enucleation. On examination, conjunctiva was injected in right eye with cells in anterior vitreous face (AVF). Fundus examination revealed a large pigmented choroidal mass temporal to macula with exudative retinal detachment. Systemic evaluation and multimodal imaging ruled out the possibility of a choroidal melanoma or metastasis, with a presumptive diagnosis of nodular posterior scleritis. Three cycles of intravenous methyl prednisolone (IVMP) with a tapering dose of oral corticosteroids showed drastic improvement in symptoms with resolution of choroidal mass - further confirming the diagnosis.

CONCLUSIONS

In cases of choroidal mass with an inflammatory component, a trial of steroids is worthwhile to prevent clinical misjudgement and devastating treatment outcomes including enucleation.

摘要

目的

报告一例表现为非典型结节性后部巩膜炎的病例,该病例类似于黑色素瘤性脉络膜黑色素瘤。

方法

描述性病例报告。

结果

一名 38 岁女性因右眼突发性视力下降、剧烈疼痛和眼红而就诊。一年前她被诊断为左眼脉络膜黑色素瘤,并接受了眼球摘除术。检查发现右眼结膜充血,前玻璃体腔有细胞(AVF)。眼底检查显示在黄斑颞侧有一大块色素性脉络膜肿块,伴有渗出性视网膜脱离。全身评估和多模态成像排除了脉络膜黑色素瘤或转移的可能性,诊断为结节性后部巩膜炎。静脉注射甲基泼尼松龙(IVMP)三个疗程,同时逐渐减少口服皮质类固醇的剂量,症状明显改善,脉络膜肿块消退——进一步证实了诊断。

结论

对于有炎症成分的脉络膜肿块,皮质类固醇的试验是值得的,可以防止临床误诊和破坏性的治疗结果,包括眼球摘除。

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