• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Addressing human factors in the recognition and management of local anaesthetic systemic toxicity.解决局部麻醉药全身毒性识别与管理中的人为因素问题。
J Perioper Pract. 2025 Oct;35(10):437-442. doi: 10.1177/17504589241264403. Epub 2024 Jul 26.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Physician anaesthetists versus non-physician providers of anaesthesia for surgical patients.外科患者的麻醉:医师麻醉师与非医师麻醉提供者的比较
Cochrane Database Syst Rev. 2014 Jul 11;2014(7):CD010357. doi: 10.1002/14651858.CD010357.pub2.
4
Injectable local anaesthetic agents for dental anaesthesia.用于牙科麻醉的注射用局部麻醉剂。
Cochrane Database Syst Rev. 2018 Jul 10;7(7):CD006487. doi: 10.1002/14651858.CD006487.pub2.
5
Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.术中局部麻醉以减轻儿童和青少年牙科治疗全身麻醉后的术后疼痛。
Cochrane Database Syst Rev. 2014 Dec 23;2014(12):CD009742. doi: 10.1002/14651858.CD009742.pub2.
6
Management of urinary stones by experts in stone disease (ESD 2025).结石病专家对尿路结石的管理(2025年结石病专家共识)
Arch Ital Urol Androl. 2025 Jun 30;97(2):14085. doi: 10.4081/aiua.2025.14085.
7
Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy.腹腔镜胆囊切除术中局部麻醉剂伤口浸润
Cochrane Database Syst Rev. 2014 Mar 12;2014(3):CD007049. doi: 10.1002/14651858.CD007049.pub2.
8
Assessment of anaesthesiologist and public hospital preparedness for the prevention and treatment of local anaesthetic systemic toxicity (LAST): a national survey.麻醉医生与公立医院对局部麻醉药全身毒性(LAST)防治的准备情况评估:一项全国性调查
Ann Med. 2025 Dec;57(1):2539306. doi: 10.1080/07853890.2025.2539306. Epub 2025 Aug 7.
9
Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults.成人围手术期持续静脉输注利多卡因用于术后疼痛及恢复
Cochrane Database Syst Rev. 2018 Jun 4;6(6):CD009642. doi: 10.1002/14651858.CD009642.pub3.
10
Pain management for women in labour: an overview of systematic reviews.分娩期女性的疼痛管理:系统评价综述
Cochrane Database Syst Rev. 2012 Mar 14;2012(3):CD009234. doi: 10.1002/14651858.CD009234.pub2.

本文引用的文献

1
Preventing Local Anesthetic Systemic Toxicity After Administration of Long-Acting Local Anesthetics.长效局部麻醉药给药后预防局部麻醉药全身毒性反应
AORN J. 2024 Feb;119(2):164-168. doi: 10.1002/aorn.14085.
2
The promise of digital healthcare technologies.数字医疗技术的前景。
Front Public Health. 2023 Sep 26;11:1196596. doi: 10.3389/fpubh.2023.1196596. eCollection 2023.
3
Reasons for resistance to change in nursing: an integrative review.护理领域中变革阻力的原因:一项综合综述
BMC Nurs. 2023 Sep 11;22(1):310. doi: 10.1186/s12912-023-01460-0.
4
Human factors in anaesthesia: a narrative review.麻醉中的人为因素:叙事性综述。
Anaesthesia. 2023 Apr;78(4):479-490. doi: 10.1111/anae.15920. Epub 2023 Jan 11.
5
Strategies to Prevent Local Anesthetic Systemic Toxicity.预防局部麻醉药全身毒性的策略。
AORN J. 2023 Jan;117(1):P10. doi: 10.1002/aorn.13860.
6
Fostering a just culture in healthcare organizations: experiences in practice.在医疗保健组织中培养公正文化:实践经验。
BMC Health Serv Res. 2022 Aug 13;22(1):1035. doi: 10.1186/s12913-022-08418-z.
7
Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update.急性护理医院预防中心静脉导管相关血流感染的策略:2022年更新
Infect Control Hosp Epidemiol. 2022 May;43(5):553-569. doi: 10.1017/ice.2022.87. Epub 2022 Apr 19.
8
Importance of non-technical skills in anaesthesia education.非技术技能在麻醉学教育中的重要性。
Indian J Anaesth. 2022 Jan;66(1):64-69. doi: 10.4103/ija.ija_1097_21. Epub 2022 Feb 3.
9
NRFit connectors in regional anaesthesia- Another step towards safe clinical practice.区域麻醉中的NRFit连接器——迈向安全临床实践的又一步。
Indian J Anaesth. 2021 Sep;65(9):701-702. doi: 10.4103/ija.ija_551_21. Epub 2021 Oct 8.
10
Human errors and their prevention in healthcare.医疗保健中的人为错误及其预防
J Anaesthesiol Clin Pharmacol. 2021 Jul-Sep;37(3):328-335. doi: 10.4103/joacp.JOACP_364_19. Epub 2021 Oct 12.

解决局部麻醉药全身毒性识别与管理中的人为因素问题。

Addressing human factors in the recognition and management of local anaesthetic systemic toxicity.

作者信息

Curtain Niamh Eb, Gugelmin-Almeida Debora

机构信息

Faculty of Health & Social Sciences, Bournemouth University, Bournemouth, UK.

出版信息

J Perioper Pract. 2025 Oct;35(10):437-442. doi: 10.1177/17504589241264403. Epub 2024 Jul 26.

DOI:10.1177/17504589241264403
PMID:39056493
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12446719/
Abstract

In the perioperative environment, local anaesthetics are commonly administered to patients to provide analgesia and anaesthesia for a large range of surgical procedures. Although rare, their use can result in systemic toxicity, which is a life-threatening complication, underscoring the importance of early recognition and prompt management to mitigate patient risks. This article evaluates the impact of human factors and other aspects such as insufficient monitoring, errors in drug administration and poor adherence to safety protocols on the development and management of local anaesthetic systemic toxicity and provides practical considerations to minimise its occurrence.

摘要

在围手术期环境中,局部麻醉剂通常用于患者,为一系列外科手术提供镇痛和麻醉。尽管其使用导致全身毒性的情况罕见,但这是一种危及生命的并发症,凸显了早期识别和及时处理以降低患者风险的重要性。本文评估了人为因素以及诸如监测不足、药物给药错误和对安全规程遵守不力等其他方面对局部麻醉剂全身毒性的发生和处理的影响,并提供了切实可行的注意事项以尽量减少其发生。