Curtain Niamh Eb, Gugelmin-Almeida Debora
Faculty of Health & Social Sciences, Bournemouth University, Bournemouth, UK.
J Perioper Pract. 2025 Oct;35(10):437-442. doi: 10.1177/17504589241264403. Epub 2024 Jul 26.
In the perioperative environment, local anaesthetics are commonly administered to patients to provide analgesia and anaesthesia for a large range of surgical procedures. Although rare, their use can result in systemic toxicity, which is a life-threatening complication, underscoring the importance of early recognition and prompt management to mitigate patient risks. This article evaluates the impact of human factors and other aspects such as insufficient monitoring, errors in drug administration and poor adherence to safety protocols on the development and management of local anaesthetic systemic toxicity and provides practical considerations to minimise its occurrence.
在围手术期环境中,局部麻醉剂通常用于患者,为一系列外科手术提供镇痛和麻醉。尽管其使用导致全身毒性的情况罕见,但这是一种危及生命的并发症,凸显了早期识别和及时处理以降低患者风险的重要性。本文评估了人为因素以及诸如监测不足、药物给药错误和对安全规程遵守不力等其他方面对局部麻醉剂全身毒性的发生和处理的影响,并提供了切实可行的注意事项以尽量减少其发生。