School of Integrated Circuits, Shandong University, Jinan 250100, China.
Biosensors (Basel). 2024 Jun 24;14(7):318. doi: 10.3390/bios14070318.
Terahertz (THz) spectroscopy has demonstrated significant potential for substance detection due to its low destructiveness and due to the abundance of molecular fingerprint absorption signatures that it contains. However, there is limited research on the fingerprint detection of substances at different temperatures. Here, we propose a THz metamaterial slit array sensor that exploits localized surface plasmons to enhance the electric field within the slit. The transmission peak frequency can be modulated via temperature adjustments. This method enables the detection of molecular absorption characteristics at multiple spectral frequency points, thereby achieving a specific and highly sensitive detection of characteristic analyte fingerprint spectra. Additionally, the sensor supports the detection of substances at multiple temperatures and sensitively identifies changes in their absorption properties as a function of temperature. Our research has employed temperature variation to achieve a highly sensitive and specific detection of trace analytes, offering a new solution for THz molecular detection.
太赫兹(THz)光谱学由于其低破坏性和包含丰富的分子指纹吸收特征,在物质检测方面显示出了巨大的潜力。然而,关于不同温度下物质的指纹检测的研究还很有限。在这里,我们提出了一种太赫兹超材料狭缝阵列传感器,它利用局域表面等离激元来增强狭缝内的电场。通过温度调节可以调制透射峰频率。这种方法可以实现对多个光谱频率点的分子吸收特性的检测,从而实现对特征分析物指纹光谱的特异性和高灵敏度检测。此外,该传感器支持在多个温度下检测物质,并能灵敏地识别其吸收特性随温度的变化。我们的研究通过温度变化实现了对痕量分析物的高灵敏度和特异性检测,为太赫兹分子检测提供了一种新的解决方案。