Institute of Biomedical Engineering & Technology, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Yiwu Research Institute of Fudan University, Zhejiang, China.
Ultrason Imaging. 2024 Nov;46(6):295-311. doi: 10.1177/01617346241265468. Epub 2024 Jul 26.
Ultrasound imaging for bone is a difficult task in the field of medical ultrasound. Compared with other phase array techniques, the synthetic aperture (SA) has a better lateral resolution but a limited imaging depth due to the limited ultrasonic energy emitted by the single emitter in each transmission. In contrast, the virtual source (VS) synthetic aperture allows a simultaneous multi-element emission and could provide a higher ultrasonic incident energy in each transmission. Therefore, the VS might achieve a high imaging quality at a deeper depth for bone imaging than the traditional SA. In this study, we proposed the virtual source phase shift migration (VS-PSM) method to achieve ultrasonic imaging of the deeper bone defect featured in the multilayer structure. The proposed VS-PSM method was validated using standard soft tissue phantom and printed bone phantom with artificial defects. The image quality was evaluated in terms of contrast-to-noise ratios (CNR) and amplitudes of scatters and defects at different imaging depths. The results showed that the VS-PSM method could achieve a high imaging quality of the soft tissues with a significant improvement in the scattering amplitude and without a significant sacrifice of the lateral and axial resolution. The PSM was superior to the DAS in suppressing the background noise in the images. Compared with the traditional SA-PSM, the VS-PSM method could image deeper bone defects at different ultrasonic frequencies, with an average improvement of 50% in CNR. In conclusion, this study demonstrated that the proposed VS-PSM method could image deeper bone defects and might help the diagnosis of bone disease using ultrasonic imaging.
超声成像是医学超声领域中的一项艰巨任务。与其他相控阵技术相比,合成孔径(SA)具有更好的横向分辨率,但由于每个发射体在每次发射中发射的超声能量有限,因此成像深度有限。相比之下,虚拟源(VS)合成孔径允许同时进行多元素发射,并在每次发射中提供更高的超声入射能量。因此,VS 可能比传统的 SA 实现更深的骨成像更高的成像质量。在这项研究中,我们提出了虚拟源相移迁移(VS-PSM)方法,以实现具有多层结构特征的更深骨缺陷的超声成像。使用标准软组织体模和带有人工缺陷的打印骨体模对所提出的 VS-PSM 方法进行了验证。根据不同成像深度处的散射和缺陷的对比度噪声比(CNR)和幅度来评估图像质量。结果表明,VS-PSM 方法可以实现软组织的高成像质量,散射幅度显著提高,而横向和轴向分辨率没有明显降低。PSM 比 DAS 更能抑制图像中的背景噪声。与传统的 SA-PSM 相比,VS-PSM 方法可以在不同的超声频率下对更深的骨缺陷进行成像,CNR 平均提高了 50%。总之,这项研究表明,所提出的 VS-PSM 方法可以对更深的骨缺陷进行成像,并且可能有助于使用超声成像诊断骨病。