Department of Thoracic Surgery and Breast Surgery, Asahikawa Medical University Hospital, Hokkaido, Asahikawa-shi, Japan.
Cancer Invest. 2024 Sep;42(8):690-696. doi: 10.1080/07357907.2024.2383930. Epub 2024 Jul 26.
Invasive cribriform carcinoma (ICC) is a type of malignant tumor with slow growth and good prognosis. The study was a single center retrospective study. The percentage of ICC among patients diagnosed with breast cancer was 0.3% (8/2454 patients). All patients tested positive for estrogen or progesterone receptors and 12.5% (1/8) patients tested positive for human epidermal growth factor receptor type2 (HER2). The present study suggests that the clinicopathological features of ICC are low-grade hormone receptor-positive luminal type with a good prognosis. However, some patients were HER2-positive and require careful follow-up.
浸润性筛状癌(ICC)是一种生长缓慢、预后良好的恶性肿瘤。本研究为单中心回顾性研究。在诊断为乳腺癌的患者中,ICC 占 0.3%(2454 例患者中的 8 例)。所有患者的雌激素或孕激素受体均呈阳性,12.5%(8 例中的 1 例)的患者人表皮生长因子受体 2(HER2)呈阳性。本研究表明,ICC 的临床病理特征为低级别激素受体阳性腔面型,预后良好。然而,部分患者为 HER2 阳性,需要密切随访。