Department of Food, Environmental and Nutritional Sciences (DeFENS), International Center for the Assessment of Nutritional Status (ICANS), University of Milan, Milan, Italy.
Department of Endocrine and Metabolic Medicine, Clinical Nutrition Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy.
PLoS One. 2024 Jul 26;19(7):e0307834. doi: 10.1371/journal.pone.0307834. eCollection 2024.
The diverse manifestations of Long-COVID have become increasingly important due to their significant impact on patients' lives. Telemedicine has emerged as an important tool for post COVID-19 follow-up. This study is part of a large cohort study involving COVID-positive patients monitored by the COD19 telemedicine platform operations center. We recontacted patients who were initially monitored from February 2020 to May 2020 to assess the presence of Long-COVID symptoms at a 2-year follow-up.
We conducted interviews to evaluate Long-COVID symptoms at the 2-year mark and investigated whether patients had contracted a second COVID-19 infection between the 1-year and 2-year follow-ups, and recorded their vaccination status.
Out of 165 patients, 139 (84%) reported symptoms at the 1-year follow-up, while only 101 (61%) reported symptoms at the 2-year follow-up. Among patients with Long-COVID symptoms at the 2-year follow-up, the majority (80, 49%) had experienced Long-COVID at the 1-year follow-up, received the SARS-CoV-2 vaccine, and had not experienced a second infection between the two follow-ups. Both having Long-COVID at the 1-year follow-up and contracting a second infection were significant risk factors for presenting with Long-COVID at the 2-year follow-up.
To the best of our knowledge, this study stands out as one of the few that includes a 2-year follow-up on Long-COVID symptoms using telemedicine. Telemedicine has proven to be an effective and innovative tool for long-term patient monitoring, early diagnosis, and treatment. Telemedicine represents a significant future challenge for healthcare.
由于长新冠对患者生活的重大影响，其多样化的表现变得越来越重要。远程医疗已成为新冠后随访的重要工具。本研究是一项大型队列研究的一部分，该研究涉及由 COD19 远程医疗平台运营中心监测的新冠阳性患者。我们对最初于 2020 年 2 月至 5 月监测的患者进行了再联系，以在 2 年随访时评估长新冠症状。
我们进行了访谈，以评估 2 年时的长新冠症状，并调查患者在 1 年和 2 年随访之间是否感染了第二次新冠病毒，并记录了他们的疫苗接种情况。
在 165 名患者中，有 139 名（84%）在 1 年随访时报告了症状，而只有 101 名（61%）在 2 年随访时报告了症状。在 2 年随访时出现长新冠症状的患者中，大多数（80 例，49%）在 1 年随访时就已经出现了长新冠，接种了 SARS-CoV-2 疫苗，并且在两次随访之间没有感染第二次新冠病毒。在 1 年随访时患有长新冠和感染第二次新冠病毒均是在 2 年随访时出现长新冠的显著风险因素。
据我们所知，这项研究是少数使用远程医疗对长新冠症状进行 2 年随访的研究之一。远程医疗已被证明是一种有效的、创新的长期患者监测、早期诊断和治疗工具。远程医疗是未来医疗保健的重大挑战。
