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马来西亚单中心横断面研究:慢性疼痛患者中广泛性焦虑障碍的患病率及相关因素。

Prevalence and factors associated with generalized anxiety disorder among patients with chronic pain: A single center cross sectional study in Malaysia.

机构信息

Department of Psychiatry, Faculty of Medicine, Universiti Teknologi MARA (UiTM), Sungai Buloh, Selangor, Malaysia.

Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA (UiTM), Sungai Buloh, Selangor, Malaysia.

出版信息

PLoS One. 2024 Jul 26;19(7):e0307992. doi: 10.1371/journal.pone.0307992. eCollection 2024.

Abstract

BACKGROUND

Managing chronic pain was not only a major challenge but also a source of significant disability associated with mental illness. Studies on generalized anxiety disorder (GAD) in chronic pain population was rather limited. This study was aimed to determine the prevalence of GAD and its associated factors among patients attending a pain clinic at a general hospital.

METHODS

This cross-sectional study recruited 201 patients. The Hospital Anxiety Depression Scale (HADS) was used to determine anxiety level. Subsequently, patients who had scored 8 and above on the HADS were interviewed using Mini International Neuropsychiatric Interview (M.I.N.I) to ascertain the diagnosis of GAD. Whilst the Numerical Rating Scale (NRS) assessed pain severity. Multiple logistic regression analysis was used to determine factors associated with GAD.

RESULTS

Among those patients with chronic pain, the prevalence of GAD was 18.9%. Gender (AOR:7.94; 95% CI:2.34, 26.93), duration of the pain (AOR:1.30; 95% CI:1.03,1.63) and pain severity (AOR:18.75; CI:1.23,285.13) were significant factors associated with GAD.

CONCLUSION

GAD is a prevalent condition among chronic pain patients.

摘要

背景

管理慢性疼痛不仅是一项重大挑战,也是与精神疾病相关的主要致残原因。针对慢性疼痛人群中广泛性焦虑障碍(GAD)的研究相当有限。本研究旨在确定在综合医院疼痛诊所就诊的患者中 GAD 的患病率及其相关因素。

方法

本横断面研究招募了 201 名患者。采用医院焦虑抑郁量表(HADS)来确定焦虑程度。随后,HADS 得分在 8 分及以上的患者使用 Mini 国际神经精神访谈(MINI)进行访谈,以确定 GAD 的诊断。而数字评分量表(NRS)评估疼痛严重程度。采用多因素逻辑回归分析确定与 GAD 相关的因素。

结果

在患有慢性疼痛的患者中,GAD 的患病率为 18.9%。性别(OR:7.94;95%CI:2.34,26.93)、疼痛持续时间(OR:1.30;95%CI:1.03,1.63)和疼痛严重程度(OR:18.75;CI:1.23,285.13)是与 GAD 相关的显著因素。

结论

GAD 在慢性疼痛患者中较为普遍。

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