Jinhua Hospital of Traditional Chinese Medicine, Jinhua, China.
The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Medicine (Baltimore). 2024 Jul 26;103(30):e39102. doi: 10.1097/MD.0000000000039102.
Femoral head necrosis is a common refractory disease in orthopedics, and shows a trend of getting younger. The occurrence of femoral head necrosis in adolescents is related to the use of glucocorticoids, autoimmune diseases, trauma, and other factors. Because adolescent patients are in the period of physical development, high activity requirements, and have fertility needs in the future, treatment is relatively difficult. Early artificial joint replacement may have problems such as wear and loosening, so total hip replacement is not the preferred treatment for adolescent patients with femoral head necrosis. This article will elaborate the research progress of femoral head necrosis in adolescents from 3 aspects, and summarize the benefits and side effects of core decompression combined with autologous stem cell transplantation in the treatment of early femoral head necrosis, so as to provide clinical ideas for the treatment of femoral head necrosis in adolescents.
股骨头坏死是骨科的一种常见难治性疾病，且呈现出年轻化的趋势。青少年股骨头坏死的发生与使用糖皮质激素、自身免疫性疾病、创伤等因素有关。由于青少年患者正处于身体发育、高活动需求以及未来生育需求的阶段，因此治疗较为困难。早期人工关节置换可能会出现磨损和松动等问题，因此全髋关节置换术并不是青少年股骨头坏死患者的首选治疗方法。本文将从 3 个方面阐述青少年股骨头坏死的研究进展，总结核心减压联合自体干细胞移植治疗早期股骨头坏死的优势及弊端，为青少年股骨头坏死的治疗提供临床思路。
