Lee Ho Seung, Kong Seong Uk, Kwon Seonil, Cho Ha-Eun, Noh Byeongju, Hwang Yong Ha, Choi Seungyeop, Kim Dohong, Han Jun Hee, Lee Tae-Woo, Jeon Yongmin, Choi Kyung Cheol
School of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
Department of Biomedical Engineering, Gachon University, Seongnam 13120, Republic of Korea.
ACS Nano. 2024 Jul 26. doi: 10.1021/acsnano.4c04374.
In the Fourth Industrial Revolution, as the connection between objects and people becomes increasingly important, interest in wearable optoelectronic device-based medical diagnosis is on the rise. Pulse oximetry sensors based on a fiber platform, which is the smallest unit of clothing, could be considered an attractive candidate for this application. In this study, red and green quantum-dot light-emitting fibers (QDLEFs) based on a 250 μm-diameter 1-dimensional fiber were successfully implemented, achieving high current efficiencies of approximately 22.46 mW/sr/A and 23.6 mW/sr/A and narrow full-width at half-maximum (FWHM) of about 33 nm, respectively. In addition, its omnidirectional flexibility was confirmed through a vertical and lateral bending test with 0.92% strain. By employing a transparent and flexible elastomer, a wearable pulse oximeter incorporating QDLEFs was successfully demonstrated for oxygen saturation level (SpO) monitoring on finger and wrist. It was demonstrated to be washable, and could be operated for up to about 18 h. Due to the elastomer and bottom emission, it exhibited excellent wear resistance characteristics in a 50 cycle reciprocating test conducted at about 2180.43 kPa with 220-grit abrasive paper sheet. A theoretical investigation based on modified photon diffusion analysis (MPDA) modeling also determined that using narrow FWHM light sources, such as QDLEFs, improves the resolution and accuracy of SpO monitoring. Accordingly, the proposed QDLEF showed distinguished potential as an all-in-one clothing type pulse oximetry.
在第四次工业革命中,随着物体与人们之间的联系变得越来越重要,基于可穿戴光电器件的医学诊断受到的关注日益增加。基于纤维平台(即衣物的最小单元)的脉搏血氧饱和度传感器可被视为该应用的一个有吸引力的候选方案。在本研究中,成功制备了基于直径为250μm的一维纤维的红色和绿色量子点发光纤维(QDLEF),分别实现了约22.46 mW/sr/A和23.6 mW/sr/A的高电流效率以及约33 nm的半高宽(FWHM)窄峰宽。此外,通过0.92%应变的垂直和横向弯曲测试证实了其全方位柔韧性。通过采用透明且柔性的弹性体,成功展示了一种集成QDLEF的可穿戴脉搏血氧仪,用于手指和手腕的血氧饱和度(SpO)监测。该脉搏血氧仪被证明可清洗,并且可运行约18小时。由于弹性体和底部发射,在使用220目砂纸在约2180.43 kPa下进行的50次循环往复测试中,它表现出优异的耐磨特性。基于改进的光子扩散分析(MPDA)模型的理论研究还确定,使用如QDLEF这样的窄FWHM光源可提高SpO监测的分辨率和准确性。因此,所提出的QDLEF作为一体化衣物型脉搏血氧仪显示出显著的潜力。