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POT1 recruits and regulates CST-Polα/primase at human telomeres.
Cell. 2024 Jul 11;187(14):3638-3651.e18. doi: 10.1016/j.cell.2024.05.002. Epub 2024 Jun 4.
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Comparison of Telomere Structure in Eukaryotes.
Arch Razi Inst. 2024 Dec 31;79(6):1365-1374. doi: 10.32592/ARI.2024.79.6.1365. eCollection 2024 Dec.
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TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhang.
Nucleic Acids Res. 2021 Dec 2;49(21):12377-12393. doi: 10.1093/nar/gkab1123.
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The human telomeric proteome during telomere replication.
Nucleic Acids Res. 2021 Dec 2;49(21):12119-12135. doi: 10.1093/nar/gkab1015.
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Human shelterin protein POT1 prevents severe telomere instability induced by homology-directed DNA repair.
EMBO J. 2020 Dec 1;39(23):e104500. doi: 10.15252/embj.2020104500. Epub 2020 Oct 19.
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Shelterin proteins and cancer.
Asian Pac J Cancer Prev. 2015;16(8):3085-90. doi: 10.7314/apjcp.2015.16.8.3085.
8
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
Nature. 2011 Mar 24;471(7339):532-6. doi: 10.1038/nature09772. Epub 2011 Mar 13.
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Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun. 2017 Apr 10;8:14928. doi: 10.1038/ncomms14928.
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Shelterin reduces the accessibility of telomeric overhangs.
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本文引用的文献

1
POT1 recruits and regulates CST-Polα/primase at human telomeres.
Cell. 2024 Jul 11;187(14):3638-3651.e18. doi: 10.1016/j.cell.2024.05.002. Epub 2024 Jun 4.
2
Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science. 2023 Aug 18;381(6659):771-778. doi: 10.1126/science.adi2436. Epub 2023 Aug 17.
3
Structures of the human CST-Polα-primase complex bound to telomere templates.
Nature. 2022 Aug;608(7924):826-832. doi: 10.1038/s41586-022-05040-1. Epub 2022 Jul 13.
4
Cryo-EM structure of the human CST-Polα/primase complex in a recruitment state.
Nat Struct Mol Biol. 2022 Aug;29(8):813-819. doi: 10.1038/s41594-022-00766-y. Epub 2022 May 16.
6
The structure of human CST reveals a decameric assembly bound to telomeric DNA.
Science. 2020 Jun 5;368(6495):1081-1085. doi: 10.1126/science.aaz9649.
7
Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.
Cell. 2012 Jul 6;150(1):39-52. doi: 10.1016/j.cell.2012.05.026. Epub 2012 Jun 28.
9
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Nature. 2007 Feb 1;445(7127):559-62. doi: 10.1038/nature05469. Epub 2007 Jan 21.
10
Pot1, the putative telomere end-binding protein in fission yeast and humans.
Science. 2001 May 11;292(5519):1171-5. doi: 10.1126/science.1060036.

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