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The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review.口服和外用螺内酯治疗雄激素性脱发的疗效与安全性:一项系统评价
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癌症治疗中皮肤毒性的管理:澳大利亚/新西兰视角

Management of Skin Toxicities in Cancer Treatment: An Australian/New Zealand Perspective.

作者信息

Ladwa Rahul, Fogarty Gerald, Chen Peggy, Grewal Gurpreet, McCormack Chris, Mar Victoria, Kerob Delphine, Khosrotehrani Kiarash

机构信息

Princess Alexandra Hospital, Ipswich Road, Woolloongabba, QLD 4102, Australia.

Faculty of Medicine, University of Queensland, Herston, QLD 4006, Australia.

出版信息

Cancers (Basel). 2024 Jul 12;16(14):2526. doi: 10.3390/cancers16142526.

DOI:10.3390/cancers16142526
PMID:39061166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11274446/
Abstract

Cancer systemic therapeutics and radiotherapy are often associated with dermatological toxicities that may reduce patients' quality of life and impact their course of cancer treatment. These toxicities cover a wide range of conditions that can be complex to manage with increasing severity. This review provides details on twelve common dermatological toxicities encountered during cancer treatment and offers measures for their prevention and management, particularly in the Australian/New Zealand context where skincare requirements may differ to other regions due to higher cumulative sun damage caused by high ambient ultraviolet (UV) light exposure. Given the frequency of these dermatological toxicities, a proactive phase is envisaged where patients can actively try to prevent skin toxicities.

摘要

癌症全身治疗和放射治疗常常伴有皮肤毒性反应,这可能会降低患者的生活质量并影响其癌症治疗进程。这些毒性反应涵盖了多种情况,随着严重程度的增加,处理起来可能会很复杂。本综述详细介绍了癌症治疗期间常见的十二种皮肤毒性反应,并提供了预防和管理措施,特别是在澳大利亚/新西兰的背景下,由于环境中高紫外线(UV)暴露导致的累积性晒伤较高,其皮肤护理要求可能与其他地区有所不同。鉴于这些皮肤毒性反应的发生频率,设想了一个积极主动的阶段,患者可以积极尝试预防皮肤毒性反应。