Aboushady Ahmed Taha, Manigart Olivier, Sow Abdourahmane, Fuller Walter, Ouedraogo Abdoul-Salam, Ebruke Chinelo, Babin François-Xavier, Gahimbare Laetitia, Sombié Issiaka, Stelling John
Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
West African Health Organization, Bobo-Dioulasso 01 BP 153, Burkina Faso.
Antibiotics (Basel). 2024 Jul 5;13(7):627. doi: 10.3390/antibiotics13070627.
Antimicrobial resistance poses a significant challenge to public health globally, leading to increased morbidity and mortality. AMR surveillance involves the systematic collection, analysis, and interpretation of data on the occurrence and distribution of AMR in humans, animals, and the environment for action. The West African Health Organization, part of the Economic Community of West African States (ECOWAS), is committed to addressing AMR in the region. This paper examines the status of AMR surveillance in ECOWAS countries using available WHO data from the TrACSS survey and GLASS enrollments. The analysis reveals that while progress has been made, significant challenges remain. Twelve of the fifteen ECOWAS countries are enrolled in GLASS, and ten have developed national action plans (NAPs) for AMR. However, there is a need to ensure all countries fully implement their NAPs, continue reporting to GLASS, and use the data for evidence-based actions and decision making. Surveillance systems for AMR and antimicrobial consumption/use vary across countries with some demonstrating limited capacity. All countries, except Cabo Verde, reported having a reference laboratory for AMR testing. Strengthening laboratory capabilities, data management and use, and multisectoral coordination are crucial for effective AMR surveillance and response. Based on the findings and the regional context, it is essential to prioritize capacity building, data utilization, and the adoption of standardized guidelines for AMR surveillance. Collaboration among ECOWAS countries, the WAHO, and international partners is essential to address AMR comprehensively. Ensuring a consistent supply of essential antimicrobial medications and reagents is vital.
抗菌素耐药性对全球公共卫生构成重大挑战，导致发病率和死亡率上升。抗菌素耐药性监测涉及系统收集、分析和解读关于人类、动物和环境中抗菌素耐药性的发生及分布的数据，以便采取行动。西非卫生组织是西非国家经济共同体（西非经共体）的一部分，致力于应对该地区的抗菌素耐药性问题。本文利用来自“全球抗菌素耐药性和使用监测系统”（GLASS）登记及“非洲抗菌素耐药性监测与应对”（TrACSS）调查的现有世界卫生组织数据，研究了西非经共体国家的抗菌素耐药性监测状况。分析表明，虽然已取得进展，但重大挑战依然存在。十五个西非经共体国家中有十二个已加入GLASS，十个国家已制定了抗菌素耐药性国家行动计划（NAPs）。然而，有必要确保所有国家全面实施其国家行动计划，继续向GLASS报告，并利用这些数据采取循证行动和进行决策。各国的抗菌素耐药性监测系统以及抗菌药物消费/使用情况各不相同，有些国家的能力有限。除佛得角外，所有国家均报告设有抗菌素耐药性检测参考实验室。加强实验室能力、数据管理与使用以及多部门协调对于有效的抗菌素耐药性监测和应对至关重要。根据研究结果和区域背景，必须优先开展能力建设、数据利用以及采用抗菌素耐药性监测的标准化指南。西非经共体国家、西非卫生组织和国际伙伴之间的合作对于全面应对抗菌素耐药性至关重要。确保基本抗菌药物和试剂的持续供应至关重要。
