Ruiz Sergio, Lee Sangkyun, Dalboni da Rocha Josue Luiz, Ramos-Murguialday Ander, Pasqualotto Emanuele, Soares Ernesto, García Eliana, Fetz Eberhard, Birbaumer Niels, Sitaram Ranganatha
Psychiatry Department, Interventional Psychiatric Unit, Interdisciplinary Center for Neurosciences, Medicine School, Pontificia Universidad Católica de Chile, Santiago 8320165, Chile.
Laboratory for Brain-Machine Interfaces and Neuromodulation, Pontificia Universidad Católica de Chile, Santiago 8320165, Chile.
Brain Sci. 2024 Jun 26;14(7):643. doi: 10.3390/brainsci14070643.
Motor intention is a high-level brain function related to planning for movement. Although studies have shown that motor intentions can be decoded from brain signals before movement execution, it is unclear whether intentions relating to mental imagery of movement can be decoded. Here, we investigated whether differences in spatial and temporal patterns of brain activation were elicited by intentions to perform different types of motor imagery and whether the patterns could be used by a multivariate pattern classifier to detect such differential intentions. The results showed that it is possible to decode intentions before the onset of different types of motor imagery from functional MR signals obtained from fronto-parietal brain regions, such as the premotor cortex and posterior parietal cortex, while controlling for eye movements and for muscular activity of the hands. These results highlight the critical role played by the aforementioned brain regions in covert motor intentions. Moreover, they have substantial implications for rehabilitating patients with motor disabilities.
运动意图是一种与运动计划相关的高级脑功能。尽管研究表明运动意图可以在运动执行前从脑信号中解码出来，但尚不清楚与运动心理意象相关的意图是否也能被解码。在此，我们研究了执行不同类型运动意象的意图是否会引发大脑激活在空间和时间模式上的差异，以及这些模式是否能被多变量模式分类器用于检测这种差异意图。结果表明，在控制眼球运动和手部肌肉活动的同时，有可能从额顶叶脑区（如运动前皮层和顶叶后皮层）获得的功能磁共振信号中，在不同类型运动意象开始之前解码出意图。这些结果突出了上述脑区在隐蔽运动意图中所起的关键作用。此外，它们对运动障碍患者的康复具有重要意义。
