Fehr Thorsten, Mehrens Sophia, Haag Marie-Christine, Amelung Anneke, Gloy Kilian
Institute for Psychology, University of Bremen, 28357 Bremen, Germany.
Center for Advanced Imaging, University of Bremen, 28357 Bremen, Germany.
Brain Sci. 2024 Jun 30;14(7):671. doi: 10.3390/brainsci14070671.
The exploration of functional resting-state brain developmental parameters and measures can help to improve scientific, psychological, and medical applications. The present work focussed on both traditional approaches, such as topographical power analyses at the signal space level, and advanced approaches, such as the exploration of age-related dynamics of source space data. The results confirmed the expectation that the third life decade would show a kind of stability in oscillatory signal and source-space-related parameters. However, from a source dynamics perspective, different frequency ranges appear to develop quite differently, as reflected in age-related sequential network communication profiles. Among other discoveries, the left anterior cingulate source location could be shown to reduce bi-directional network communication in the lower alpha band, whereas it differentiated its uni- and bidirectional communication dynamics to sub-cortical and posterior brain locations. Higher alpha oscillations enhanced communication dynamics between the thalamus and particularly frontal areas. In conclusion, resting-state data appear to be, at least in part, functionally reorganized in the default mode network, while quantitative measures, such as topographical power and regional source activity, did not correlate with age in the third life decade. In line with other authors, we suggest the further development of a multi-perspective approach in biosignal analyses.
对静息态大脑功能发育参数和测量方法的探索有助于改进科学、心理学和医学应用。目前的工作既关注传统方法，如信号空间层面的地形功率分析，也关注先进方法，如源空间数据与年龄相关动态变化的探索。结果证实了这样的预期：在生命的第三个十年，振荡信号和源空间相关参数会呈现出一种稳定性。然而，从源动态角度来看，不同频率范围的发育情况似乎差异很大，这在与年龄相关的序列网络通信概况中有所体现。在其他发现中，左侧前扣带回源位置在较低α频段会减少双向网络通信，而它在与皮质下和大脑后部位置的单向和双向通信动态方面存在差异。较高的α振荡增强了丘脑与特别是额叶区域之间的通信动态。总之，静息态数据似乎至少在默认模式网络中部分地进行了功能重组，而地形功率和区域源活动等定量测量在生命的第三个十年与年龄并无关联。与其他作者一致，我们建议在生物信号分析中进一步发展多视角方法。
