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下丘脑室旁核中含催产素神经元传入突触输入的超微结构研究。

Ultrastructural studies on the afferent synaptic input to oxytocin-containing neurons in the paraventricular nucleus of the hypothalamus.

作者信息

Piekut D T

出版信息

J Ultrastruct Res. 1985 Jan;90(1):71-9. doi: 10.1016/0889-1605(85)90117-x.

DOI:10.1016/0889-1605(85)90117-x
PMID:3906152
Abstract

A diverse afferent synaptic input to immunostained oxytocin magnocellular neurons of the paraventricular nucleus of the rat hypothalamus is described. By electron microscopy, immunoreactive material is present within cell bodies and neuronal processes and it is associated primarily with neurosecretory granules and granular endoplasmic reticulum. Afferent axon terminals synapse on perikarya, dendritic processes, and possibly axonal processes of oxytocin-containing neurons. The presynaptic elements of the synaptic complexes contain clear spherical vesicles, a mixture of clear spherical and ellipsoidal vesicles, or a mixture of clear and dense-centered vesicles. The postsynaptic membranes of oxytocinergic cells frequently show a prominent coating of dense material on the cytoplasmic face which gives the synaptic complex a marked asymmetry.

摘要

本文描述了对大鼠下丘脑室旁核中经免疫染色的催产素大细胞神经元的多种传入突触输入。通过电子显微镜观察,免疫反应性物质存在于细胞体和神经突起内,并且主要与神经分泌颗粒和粗面内质网相关。传入轴突终末与含催产素神经元的胞体、树突突起以及可能的轴突突起形成突触。突触复合体的突触前成分包含清亮球形小泡、清亮球形和椭圆形小泡的混合物,或清亮和致密中心小泡的混合物。催产素能细胞的突触后膜在细胞质面经常显示出一层明显的致密物质涂层,这使得突触复合体具有明显的不对称性。

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