Cosoreanu Andrada, Rusu Emilia, Rusu Florin, Stanciu Silviu, Ungureanu Ioana, Donici Marius, Visinescu Alexandra, Enache Georgiana, Radulian Gabriela
Department of Diabetes, Nutrition and Metabolic Diseases, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
"Doctor Carol Davila" Central Military University Emergency Hospital, 010825 Bucharest, Romania.
Biomedicines. 2024 Jun 26;12(7):1422. doi: 10.3390/biomedicines12071422.
The Roma population is Europe's largest ethnic minority, yet data on the prevalence of non-communicable diseases remain scarce in medical literature. This study aimed to compare the clinical and metabolic particularities of a Roma population with diabetes with a group of non-Roma. We conducted an observational, transversal study and evaluated 808 adult patients with diabetes mellitus, from a tertiary diabetes care hospital. The prevalence of metabolic syndrome was high among both groups, 94.3% in the Roma patients and 89.1% in the non-Roma. A slightly higher mean value of the triglyceride-glucose (TyG) index was observed among the Roma group (10.07 ± 0.71 versus 9.71 ± 0.82). Among the non-Roma, variables that were significantly associated with the TyG index were glycated hemoglobin (HbA1c), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-c), and low-density lipoprotein-cholesterol (LDL-c), while among the Roma, HbA1c and HDL-c were correlated with this index. There were no differences concerning myocardial infarction; however, the number of patients with a history of stroke was 2.1 times higher in the Roma group compared to the non-Roma group. The prevalence of cardiovascular risk factors, cardiovascular disease, and microvascular complications among the study's Roma population are quite significant, underscoring the importance of ethnic disparities in approaching healthcare management strategies.
罗姆人是欧洲最大的少数民族,但医学文献中关于非传染性疾病患病率的数据仍然很少。本研究旨在比较患有糖尿病的罗姆人群与非罗姆人群的临床和代谢特征。我们进行了一项观察性横断面研究,对一家三级糖尿病护理医院的808例成年糖尿病患者进行了评估。两组患者的代谢综合征患病率都很高,罗姆患者为94.3%,非罗姆患者为89.1%。罗姆组的甘油三酯-葡萄糖(TyG)指数平均值略高(10.07±0.71对9.71±0.82)。在非罗姆人群中,与TyG指数显著相关的变量有糖化血红蛋白(HbA1c)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-c)和低密度脂蛋白胆固醇(LDL-c),而在罗姆人群中,HbA1c和HDL-c与该指数相关。心肌梗死方面没有差异;然而,罗姆组有中风病史的患者数量是非罗姆组的2.1倍。本研究中罗姆人群中心血管危险因素、心血管疾病和微血管并发症的患病率相当高,这突出了在制定医疗管理策略时种族差异的重要性。