Mazzella Antonio, Orlandi Riccardo, Maiorca Sebastiano, Uslenghi Clarissa, Chiari Matteo, Bertolaccini Luca, Casiraghi Monica, Lo Iacono Giorgio, Girelli Lara, Spaggiari Lorenzo
Division of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Division of Oncology and Hemato-Oncology, University of Milan, 20141 Milan, Italy.
Biomedicines. 2024 Jul 12;12(7):1554. doi: 10.3390/biomedicines12071554.
Pulmonary cancer is often associated with systemic inflammation and poor nutritional status and these two aspects are strongly correlated and related to the scarce infiltration of a tumor by immune cells. We reviewed all English literature reviews from 2000 to 2024 from PubMed, Scopus and Google Scholar, including original articles, review articles, and metanalyses. We excluded non-English language articles and case reports/case series. Generally speaking, nutritional and inflammatory status largely affect medium and long-term prognosis in lung cancer patients. A correct stratification of patients could improve their preoperative general functional nutritional and inflammatory status, minimizing, therefore, possible treatment complications and improving long-term prognosis.
肺癌常与全身炎症和营养不良状态相关，这两个方面密切相关，且与肿瘤免疫细胞浸润稀少有关。我们回顾了2000年至2024年来自PubMed、Scopus和谷歌学术的所有英文文献综述，包括原创文章、综述文章和荟萃分析。我们排除了非英语文章以及病例报告/病例系列。一般来说，营养和炎症状态在很大程度上影响肺癌患者的中长期预后。对患者进行正确分层可以改善其术前的一般功能营养和炎症状态，从而最大限度地减少可能的治疗并发症并改善长期预后。
