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全基因组鉴定与基因家族的进化和突变分析。

Genome-Wide Identification and Evolutionary and Mutational Analysis of the Gene Family.

机构信息

College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.

Anhui Provincial Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding, Anhui Agricultural University, Hefei 230036, China.

出版信息

Genes (Basel). 2024 Jul 9;15(7):897. doi: 10.3390/genes15070897.


DOI:10.3390/genes15070897
PMID:39062676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11275364/
Abstract

is known for its tolerance of coarse grains, adaptability, high temperature, humidity, and disease resistance. Primarily, cattle are raised for their meat and milk, and pinpointing genes associated with traits relevant to meat production can enhance their overall productivity. The aim of this study was to identify the genome, analyze the evolution, and explore the function of the gene family in to provide a new molecular target for breeding in meat-quality-trait cattle. In this study, 44 genes were identified from the genome database of five species using bioinformatics technology, indicating that the genetic relationships of bovids were similar. The and protein sequences of the five animals were highly consistent. In general, the gene of the buffalo corresponds to the domestic cattle. In summary, there are differences in affinity between the family genes of buffalo and domestic cattle in the , , and subfamilies. We believe that has an effect on the growth traits of buffalo and domestic cattle. The gene is conserved in the evolution of buffalo and domestic animals and may be a key gene regulating the growth of B. taurus. The subfamily affects coat color, reproductive performance, and milk production performance in cattle. The subfamily had an effect on the milk fat percentage of B. taurus. The results provide a theoretical basis for understanding the evolutionary, structural, and functional characteristics of the family members of and for molecular genetics and the breeding of meat-production species.

摘要

是一种以能耐受粗饲料、适应性强、耐高温高湿、抗病力强而著称的动物。牛主要用于生产肉类和牛奶,而鉴定与肉类生产相关的性状相关的基因可以提高其整体生产力。本研究旨在识别基因组,分析进化,并探索基因家族在中的功能,为肉质性状牛的育种提供新的分子靶标。在这项研究中,使用生物信息学技术从五个物种的基因组数据库中鉴定出 44 个基因,表明牛科动物的遗传关系相似。五种动物的和蛋白序列高度一致。总的来说,水牛的基因与家牛相对应。综上所述,水牛和家牛的基因家族在、、和亚家族之间存在亲和力差异。我们认为基因对水牛和家牛的生长性状有影响。基因在水牛和家畜的进化过程中是保守的,可能是调节 B. taurus 生长的关键基因。亚家族影响牛的毛色、繁殖性能和产奶性能。亚家族对 B. taurus 的乳脂百分比有影响。这些结果为了解和的基因家族成员的进化、结构和功能特征提供了理论依据,也为分子遗传学和肉质生产物种的育种提供了理论依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/9d32ddfda00d/genes-15-00897-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/9bad42e14ab6/genes-15-00897-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/61d97a8a089b/genes-15-00897-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/6b74d0067801/genes-15-00897-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/e3f524e3a192/genes-15-00897-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/e36cd4279879/genes-15-00897-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/2540f6ab5d5e/genes-15-00897-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/cde485414540/genes-15-00897-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/9d32ddfda00d/genes-15-00897-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/9bad42e14ab6/genes-15-00897-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/61d97a8a089b/genes-15-00897-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/6b74d0067801/genes-15-00897-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/e3f524e3a192/genes-15-00897-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/e36cd4279879/genes-15-00897-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/2540f6ab5d5e/genes-15-00897-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/cde485414540/genes-15-00897-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d121/11275364/9d32ddfda00d/genes-15-00897-g008.jpg

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Genome-Wide Identification and Evolutionary and Mutational Analysis of the Gene Family.

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[3]
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[6]
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[7]
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[8]
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[10]
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本文引用的文献

[1]
Pax4 in Health and Diabetes.

Int J Mol Sci. 2023-5-5

[2]
Molecular mechanisms of adaptive evolution in wild animals and plants.

Sci China Life Sci. 2023-3

[3]
disease models for aniridia.

Indian J Ophthalmol. 2022-12

[4]
An overview of PAX1: Expression, function and regulation in development and diseases.

Front Cell Dev Biol. 2022-10-28

[5]
PAX8 as a Potential Target for Ovarian Cancer: What We Know so Far.

Onco Targets Ther. 2022-10-21

[6]
The regenerative potential of Pax3/Pax7 on skeletal muscle injury.

J Genet Eng Biotechnol. 2022-10-17

[7]
Favored single nucleotide variants identified using whole genome Re-sequencing of Austrian and Chinese cattle breeds.

Front Genet. 2022-9-27

[8]
PAX Genes in Cardiovascular Development.

Int J Mol Sci. 2022-7-12

[9]
The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17.

Sci Signal. 2022-4-5

[10]
Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.

Genesis. 2021-11

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