Faculty of Chemistry, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego St. 8, 61-614 Poznan, Poland.
Int J Mol Sci. 2024 Jul 19;25(14):7894. doi: 10.3390/ijms25147894.
A method for the reduction of aldehydes with pinacolborane catalyzed by pincer cobalt complexes based on a triazine backbone is developed in this paper. The presented methodology allows for the transformation of several aldehydes bearing a wide range of electron-withdrawing and electron-donating groups under mild conditions. The presented procedure allows for the direct one-step hydrolysis of the obtained intermediates to the corresponding primary alcohols. A plausible reaction mechanism is proposed.
本文开发了一种基于三嗪骨架的钳形钴配合物催化频哪醇硼烷还原醛的方法。所提出的方法允许在温和条件下转化带有广泛吸电子和供电子基团的几种醛。所提出的程序允许直接将获得的中间体一步水解成相应的伯醇。提出了一个合理的反应机理。
