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正常男性和女性之间胰岛素敏感性的差异。

Differences in insulin sensitivity between normal men and women.

作者信息

Hale P J, Wright J V, Nattrass M

出版信息

Metabolism. 1985 Dec;34(12):1133-8. doi: 10.1016/0026-0495(85)90159-3.

DOI:10.1016/0026-0495(85)90159-3
PMID:3906353
Abstract

An incremental intravenous low-dose insulin infusion has been used to examine differences in insulin sensitivity between normal young men and women. Fasting blood glucose concentration did not differ significantly at the start of the infusion but women had significantly higher plasma insulin and C-peptide concentrations. Similar changes in blood glucose occurred during insulin infusion but insulin concentrations were higher in women. Blood total ketone bodies and alanine were lower in women over the four hours of infusion. Significant differences were found between normal men and women for the effect of insulin upon blood glucose concentration.

摘要

采用递增式静脉注射低剂量胰岛素输注法来研究正常年轻男性和女性之间胰岛素敏感性的差异。输注开始时,空腹血糖浓度无显著差异,但女性的血浆胰岛素和C肽浓度显著更高。胰岛素输注期间血糖出现了类似变化,但女性的胰岛素浓度更高。在输注的四个小时内,女性的血液总酮体和丙氨酸含量较低。在胰岛素对血糖浓度的影响方面,正常男性和女性之间存在显著差异。

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Metabolism. 1985 Dec;34(12):1133-8. doi: 10.1016/0026-0495(85)90159-3.
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