Katsimperis Stamatios, Pinitas Alexandros, Zerva Maria, Bellos Themistoklis, Manolitsis Ioannis, Feretzakis Georgios, Verykios Vassilios S, Kyriazis Ioannis, Neofytou Panagiotis, Kapsalos Sotirios, Deligiannis Panagiotis, Triantafyllou Panagiotis, Juliebø-Jones Patrick, Somani Bhaskar, Mitsogiannis Iraklis, Tzelves Lazaros
Second Department of Urology, Sismanoglio Hospital, National and Kapodistrian University of Athens, 15126 Athens, Greece.
Department of Urology, General Hospital of Athens "G. Gennimatas", 11527 Athens, Greece.
Life (Basel). 2024 Jul 11;14(7):868. doi: 10.3390/life14070868.
Prostate cancer is the second most common cancer among men, with many treatment modalities available for patients, such as radical prostatectomy, external beam radiotherapy, brachytherapy, high-intensity focused ultrasound, cryotherapy, electroporation and other whole-gland or focal ablative novel techniques. Unfortunately, up to 60% of men with prostate cancer experience recurrence at 5 to 10 years. Salvage radical prostatectomy can be offered as an option in the setting of recurrence after a primary non-surgical treatment. However, the complexity of salvage radical prostatectomy is considered to be greater than that of primary surgery, making it the least popular treatment of choice. With the wide use of robotic platforms in urologic oncologic surgery, salvage radical prostatectomy has attracted attention again because, compared to past data, modern series involving salvage Robot-Assisted Radical Prostatectomy have shown promising results. In this narrative literature review, we comprehensively examined data on salvage radical prostatectomy. We investigated the correlation between the different types of primary prostate cancer therapy and the following salvage radical prostatectomy. Furthermore, we explored the concept of a robotic approach and its beneficial effect in salvage surgery. Lastly, we emphasized several promising avenues for future research in this field.
前列腺癌是男性中第二常见的癌症，有多种治疗方式可供患者选择，如根治性前列腺切除术、外照射放疗、近距离放射治疗、高强度聚焦超声、冷冻疗法、电穿孔以及其他全腺或局部消融新技术。不幸的是，高达60%的前列腺癌男性患者在5至10年会出现复发。挽救性根治性前列腺切除术可作为初次非手术治疗后复发情况下的一种选择。然而，挽救性根治性前列腺切除术的复杂性被认为大于初次手术，这使其成为最不受欢迎的治疗选择。随着机器人平台在泌尿外科肿瘤手术中的广泛应用，挽救性根治性前列腺切除术再次受到关注，因为与过去的数据相比，涉及挽救性机器人辅助根治性前列腺切除术的现代系列研究已显示出有前景的结果。在这篇叙述性文献综述中，我们全面审查了挽救性根治性前列腺切除术的数据。我们研究了不同类型的原发性前列腺癌治疗与后续挽救性根治性前列腺切除术之间的相关性。此外，我们探讨了机器人手术方法的概念及其在挽救性手术中的有益效果。最后，我们强调了该领域未来研究的几个有前景的方向。
