Mora Sara, Gazzarata Roberta, Blobel Bernd, Murgia Ylenia, Giacomini Mauro
UO Information and Communication Technologies, Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Healthropy Società a Responsabilità Limitata (S.R.L.), 17100 Savona, Italy.
J Pers Med. 2024 Jun 24;14(7):676. doi: 10.3390/jpm14070676.
Communication and cooperation are fundamental for the correct deployment of P5 medicine, and this can be achieved only by correct comprehension of semantics so that it can aspire to medical knowledge sharing. There is a hierarchy in the operations that need to be performed to achieve this goal that brings to the forefront the complete understanding of the real-world business system by domain experts using Domain Ontologies, and only in the last instance acknowledges the specific transformation at the pure information and communication technology level. A specific feature that should be maintained during such types of transformations is versioning that aims to record the evolution of meanings in time as well as the management of their historical evolution. The main tool used to represent ontology in computing environments is the Ontology Web Language (OWL), but it was not created for managing the evolution of meanings in time. Therefore, we tried, in this paper, to find a way to use the specific features of Common Terminology Service-Release 2 (CTS2) to perform consistent and validated transformations of ontologies written in OWL. The specific use case managed in the paper is the Alzheimer's Disease Ontology (ADO). We were able to consider all of the elements of ADO and map them with CTS2 terminological resources, except for a subset of elements such as the equivalent class derived from restrictions on other classes.
沟通与合作是正确部署P5医学的基础，而这只有通过正确理解语义才能实现，从而有望实现医学知识共享。为实现这一目标而需要执行的操作存在一个层次结构，这使得领域专家使用领域本体对现实世界业务系统的全面理解处于首要位置，并且仅在最后才认可纯信息和通信技术层面的特定转换。在这类转换过程中应保持的一个特定特性是版本控制，其目的是及时记录意义的演变以及对其历史演变的管理。在计算环境中用于表示本体的主要工具是本体网络语言（OWL），但它并非为及时管理意义的演变而创建。因此，在本文中，我们试图找到一种方法，利用通用术语服务第2版（CTS2）的特定特性，对用OWL编写的本体进行一致且经过验证的转换。本文中处理的具体用例是阿尔茨海默病本体（ADO）。我们能够考虑ADO的所有元素，并将它们与CTS2术语资源进行映射，但有一部分元素除外，比如从对其他类的限制派生而来的等价类。
